Can Martial Arts Training Make a Difference to Mental Health?

Matching Movement to the Individual Through Regulation, Agency and Meaning

Chris People and Daniel Mirea (23 October 2026)
| The NeuroAffective-CBTยฎ Journal |

Introduction

Combat training and mental health hardly seem to belong in the same sentence. The connection is counterintuitive. Combat suggests aggression, confrontation and the possibility of harm. Concerns about injury, including brain injury in activities involving head contact, are real and deserve attention (Neidecker et al., 2019). Why, then, consider martial arts within a discussion of psychological wellbeing?

To a keen observer, the answer may emerge through the training itself. What becomes apparent is how much attention is given to the art: learning movement, judging distance, coordinating effort, responding to another person and exercising control. In a supportive training environment, these abilities develop gradually, with the intensity and physical demands adjusted as the participant gains familiarity and skill.

Martial arts also have a substantial interpersonal dimension. Individual practice is important, but partner exercises introduce something different: another person whose movement, timing and response cannot always be fully predicted. The participant must attend, interpret and act while remaining aware of their own reactions. They may need to communicate a limit, request a slower pace, accept correction or manage the frustration of getting something wrong.

Breathing is often part of this learning. In some traditions, explicit instruction in breathing accompanies the development of posture, movement and control from an early stage. Japanese martial traditions may direct focused attention towards the hara, while Chinese practices such as Tai Chi emphasise the lower dantian, traditionally understood as a centre of vital energy (Mai, 2015; National Qigong Association, 2025). These concepts provide ways of organising attention around the abdomen, breathing and coordinated movement. Breathing becomes something to notice and coordinate with action, particularly as effort and intensity change.

Figure 1: Karate meditation (mokusล): bringing attention to the hara (the lower abdomen) through an upright, relaxed posture and gentle abdominal breathing.

Attention, bodily awareness, breathing, gradual engagement with discomfort and responsiveness to others are also familiar concerns within mindfulness and emotional regulation approaches. Their presence in martial arts makes the clinical connection worth exploring. What might a participant be learning psychologically while practising physically? Could these experiences be connected more deliberately with therapeutic goals?

Our observations and individual experiences suggest that participants can learn more than the execution of a technique. Someone who initially responds with excessive tension, hurried movement or withdrawal may gradually become more able to pause, direct attention, adjust effort and choose what to do next. Another may discover that asking for help or expressing a boundary allows participation to continue. These experiences may acquire psychological significance even when neither instructor nor participant describes them in therapeutic language.

From a NeuroAffective-CBT perspective, lifestyle interventions are an essential part of promoting health and resilience. We propose that appropriately selected martial arts training may provide a practical setting for rehearsing regulation and agency. The relevant learning will differ between individuals. It may involve remaining engaged while uncomfortable, responding less harshly to mistakes, exercising restraint or recognising when to stop. These possibilities depend on the training environment, the quality of instruction and the meaning the person gives to participation.

Matching movement to the individual is therefore central. Preferences, physical capacity, cultural meaning, access and recovery all influence whether an activity is suitable and sustainable. The same exercise may offer one person an experience of capability while becoming another demand through which someone else judges or punishes themselves. Understanding that difference belongs within therapeutic formulation.

This selective narrative review brings together exercise and martial arts research with clinical reasoning and observations from training. Drawing on NeuroAffective-CBT alongside established cognitive behavioural approaches, we examine how chosen and adapted participation might support attention, coping self-instruction, assertiveness, mastery and belonging. A hypothetical clinical illustration shows how physical practice can be connected with a specific prediction, collaborative review and an experiment outside training.

The wider exercise literature supports therapeutic relevance, while evidence specific to martial arts remains heterogeneous. Our observations inform the proposed applications rather than establish their effectiveness. The question is how particular forms of training, matched to the individual and delivered within suitable conditions, might support mental health and whether what is learned during practice becomes available in everyday life.

Keywords: martial arts; combat sports; lifestyle interventions; cognitive behavioural therapy; NeuroAffective-CBT; emotional regulation; agency; psychological flexibility; therapeutic learning.

Martial Arts and the Cultivation of Mind and Body

Organised combat practices have a documented history extending across millennia and cultures. Wrestling entered the ancient Olympic programme in 708 BCE, boxing in 688 BCE and pankration, which combined striking and wrestling, in 648 BCE. These dates concern their inclusion in the Games rather than the origins of combat practice, but they demonstrate the longstanding place of fighting skills within organised physical culture (Foundation of the Hellenic World, n.d.).

The history of Chinese martial arts provides a further connection between physical practice, cultural meaning and self-cultivation. Shahar (2008) documents the involvement of Shaolin monks in seventh-century military events and traces the subsequent development of their martial traditions. This history encompasses armed and unarmed practices, religious commitments and relationships with political institutions. Later developments also connected martial practice with therapeutic purposes. Shaolin represents one important tradition within a diverse history, illustrating how fighting skills could become associated with broader understandings of health, discipline and personal development.

In the twentieth century, Bruce Lee brought the relationship between martial practice and personal philosophy to a wide international audience. His reflections emphasised adaptability, self-expression and learning through experience. His water metaphor presented responsiveness as an alternative to rigidly imposing a predetermined form. These ideas offer a philosophical connection with contemporary interests in psychological flexibility and agency, although Lee was articulating a philosophy of practice rather than a clinical treatment model (Bruce Lee Enterprises, n.d.).

Accounts of Leeโ€™s recovery following a serious back injury add a personal dimension to this relationship. His family describes pain and emotional difficulty, extensive study, rest and a cautious return to movement. This account illustrates purposeful engagement with physical limitation, bringing reflection, learning and action together. It remains a biographical account rather than evidence that determination or self-instruction alone repaired the injury (Bruce Lee Enterprises, 2017).

Clinical interest in these connections also has an established history. Fuller (1988) discussed parallels between martial arts and psychotherapeutic concepts, including possible clinical applications. Twemlow and Sacco (1998) described therapeutic applications with adolescents presenting with violent behaviour. These contributions provide a foundation for asking how particular experiences within training might become relevant to an individualโ€™s psychological difficulties and treatment goals.

Beyond the instruction to exercise

Recommending exercise can leave the main therapeutic problem untouched. A person may understand that movement could help and still feel unable to enter a gym, tolerate being a beginner or return after a difficult first session. Shame, fatigue, anticipated judgement and practical barriers can make an apparently simple recommendation difficult to act upon.

Clinical work therefore needs to address how participation becomes possible and what the person learns through it. A correction might be interpreted as evidence of inadequacy or as ordinary assistance in learning. Asking for a pause might feel humiliating or become an experience of effective choice.

The same activity can serve different functions. Training may support curiosity and connection, reinforce punitive standards or provide temporary escape from distress. Its therapeutic significance depends on the personโ€™s formulation and experience. Salkovskis et al. (2023) describe therapy in terms of a shared understanding that is tested to enable more flexible responding. Applied to movement, this directs attention to the expectations being examined and the responses being practised.

Established approaches such as graded engagement, behavioural experiments and coping rehearsal provide methods for connecting physical practice with psychological learning. NeuroAffective-CBT offers one organising perspective for considering bodily regulation, protective responses and embodied rehearsal within this work.

Scope and approach

This selective narrative review is intended primarily for clinicians working with adults. Sources are brought together according to their relevance to exercise outcomes, martial arts and boxing, participation and candidate psychological processes. Systematic reviews and meta-analyses inform the evidence overview; selected trials and conceptual publications address particular clinical questions. The synthesis is purposive and does not claim exhaustive coverage or an independent formal quality appraisal.

General exercise findings are distinguished from evidence concerning particular disciplines and interventions. Outcomes are also distinguished from the mechanisms proposed to explain them. NeuroAffective-CBT publications provide conceptual and practitioner perspectives rather than independent empirical validation of the integrated approach.

The clinical proposals additionally draw on the authorsโ€™ observations and individual experiences of training. These inform hypothesis development rather than constitute systematically collected outcome data. The worked illustration is hypothetical, and no original patient data are reported.

What participants actually do

Martial arts and combat sports overlap, but neither label defines a uniform intervention. Traditional forms, non-contact boxing, recreational grappling and competitive mixed martial arts involve different movements, expectations and exposures. A practice may emphasise cultural tradition, self-defence, fitness or competition.

For clinical interpretation, important distinctions concern contact, sparring, exertion, instruction and freedom to stop. Shadowboxing and pad work can use striking movements without participants receiving blows. Grappling involves close physical contact and its own injury exposures. Recreational training and competition can differ substantially even within one club.

The learning environment matters alongside these physical ingredients. An instructor who welcomes questions and adapts tasks creates different opportunities from one who treats uncertainty or stopping as weakness. Community membership, traditional philosophy and shared rituals may matter in some settings and be absent in others.

An individualised recommendation therefore needs to specify what the person will do, with whom, under which conditions and for what purpose. The clinical applications discussed here concern mainly recreational training and adapted non-contact activities. Contact and competition remain separate choices rather than necessary stages of therapeutic progress.

What the exercise evidence supports

Physical activity has a substantial evidence base in mental health. Singh et al. (2023) brought together 97 systematic reviews covering 1,039 trials and 128,119 participants, reporting improvements in depression, anxiety and psychological distress across varied adult populations. However, 77 reviews received a critically low AMSTAR-2 methodological quality rating. These ratings concern the reviews rather than 77 individual trials.

Noetel et al. (2024) found benefits for several exercise modalities in depression, including walking or jogging, yoga and strength training, with confidence in estimates limited by study quality and other uncertainties. Gordon et al. (2018) identified an average reduction in depressive symptoms across 33 resistance-training trials involving 1,877 participants.

The evidence supports considering several forms of movement while leaving their selection and delivery open to individual planning. An advantage over inactivity or usual care may reflect structure, encouragement, expectation and social contact as well as exertion. Comparison with another credible activity asks a more specific question about relative benefit.

White et al. (2024) reviewed 247 studies examining mediators and moderators of the relationship between physical activity and mental health. Their synthesis identified support for self-esteem, self-efficacy, physical self-worth and social connection, with more qualified support for mastery and mindfulness. Most included studies were observational. These findings identify plausible processes for investigation while leaving uncertainty about causal pathways in an individual client.

Evidence specific to martial arts and boxing

Moore et al. (2020) synthesised 14 studies and reported a small pooled benefit for wellbeing and a moderate pooled effect on internalising mental health outcomes. Heterogeneity was substantial, particularly for internalising outcomes, and the pooled aggression finding was not statistically significant.

Ciaccioni et al. (2024) reviewed 72 observational adult studies, comprising 70 cross-sectional and two longitudinal studies. Findings varied across self-related, emotional and cognitive outcomes. The designs limit conclusions about whether differences resulted from training, pre-existing characteristics or continued participation by people who found the activity helpful.

Non-contact boxing is a closer comparison for interventions using pads, bags and combinations. Bozdarov et al. (2023) identified 16 studies across diverse populations and delivery formats. In 56%, boxing was supplemented by components such as mentoring, mindfulness or psychological strategies. The review maps promising applications, but the mixture of designs and combined interventions prevents a firm estimate of boxingโ€™s independent contribution.

Weiss et al. (2025) provide a recent clinical example. Their 24-person pilot examined taekwondo and mindfulness within a dialectical behaviour therapy intensive outpatient programme. Participants reported favourable acceptability and immediate affective changes. The small within-subject study, conducted during ongoing treatment, supports feasibility and further investigation.

Together, these findings support studying specified practices in defined contexts. They leave open which components contribute to change and how outcomes compare with other meaningful activities.

Lifestyle interventions within NeuroAffective-CBT

Lifestyle interventions address recurring conditions of daily life that affect wellbeing and participation. Sleep, movement, nutrition, hydration and recovery can influence one another. Fatigue may reduce the capacity to attend a class, while an excessively demanding training schedule may interfere with rest. These conditions belong within formulation when they contribute to difficulties or limit engagement with treatment.

Within NeuroAffective-CBT (NA-CBT), TED refers to Tirednessโ€“Exerciseโ€“Diet. Mireaโ€™s exercise discussion emphasises individualisation and meaningful participation (Mirea, 2025a), while the applied TED account places sleep, movement and nutrition within therapeutic planning (Mirea, 2025b). Practical questions include whether the person is sufficiently rested, whether the activity fits their capacity and whether training supports daily life or becomes another demand they feel compelled to meet.

Mireaโ€™s (2026) Pendulum-Effect account describes avoidance, overcompensation and capitulation as protective responses within a formulation concerned with shame. In training, these might appear as withdrawing when mistakes become visible, exercising punitively to prove worth or accepting an identity of permanent incapability. Embodied rehearsal offers a proposed way of practising a different response while difficult experience remains present.

This formulation helps distinguish occasions when demands should be reduced from occasions when a prediction maintaining avoidance could usefully be tested. Rest and adaptation may be appropriate on one occasion; on another, the useful learning may be that discomfort is compatible with chosen action.

Meichenbaumโ€™s Roadmap to Resilience places physical resources alongside interpersonal, emotional, cognitive, behavioural and spiritual resources (Meichenbaum, n.d.). This broader account keeps strengths, relationships and meaning visible alongside physical capability.

Matching movement to the individual

Activity selection begins with interests and circumstances. What has the person enjoyed previously? Would they prefer technical learning, rhythm, independent practice, cooperation or competition? What does a particular sport represent to them? Physical health, disability and previous injury matter alongside cultural identity, cost, transport and the available training environment.

The useful psychological question is often what the person needs an opportunity to practise. Achievable progression may help someone who expects failure. A supportive class may provide opportunities to be seen trying and receive feedback. Partner work might allow someone to express a preference, while regular shared activity may offer structure and repeated contact to someone experiencing isolation.

These possibilities do not prescribe a sport for a diagnosis. One person with social anxiety may appreciate interaction organised around a shared task; another may initially prefer predictable individual instruction. Someone seeking confidence may find a suitable opportunity in martial arts, dance, climbing or resistance training. Formulation clarifies what confidence means and how the setting might help develop it.

Personal meaning and enjoyment also matter for continuation. Teixeira et al. (2012) reviewed 66 studies of exercise through self-determination theory. Their findings supported relationships between autonomous motivation and participation, with enjoyment and intrinsic motivation particularly relevant to longer-term adherence. Much of the evidence was observational.

Interest may develop through skill, companionship or discovering that movement feels different from what was anticipated. Initial discomfort does not necessarily indicate a poor match, while persistent difficulty should remain open to review. Choosing another instructor, format or activity can be a successful outcome of collaborative planning.

Why martial arts may be a useful resource

Martial arts can bring technical learning, bodily effort and interpersonal negotiation into the same activity. Depending on the practice, participants must manage distance, coordinate movement, respond to another person and communicate the intensity they are willing to accept. These features can make questions of capability, control and boundaries immediately available for reflection.

Their significance remains individual. Someone who habitually withdraws may value discovering that they can take up space and act decisively. A person who overcompensates through excessive effort may benefit from practising restraint, accepting correction or stopping at an agreed point. Another may find predictable partner work an accessible route into cooperation and connection.

These are proposed learning opportunities. Their usefulness depends on preference, instruction and interpretation. The range of available formats also allows adaptation: individual non-contact practice, recreational group training and partner exercises need not involve the same demands.

The clinical rationale rests on the fit between these opportunities and the personโ€™s formulation. Martial practice becomes informative when it allows relevant responses to be practised and reviewed.

Confidence, shame, assertiveness and responses to mistakes

Confidence may develop through supported action. A simple movement becomes a short combination, and repetition makes progress visible. Someone expecting complete failure may discover that they can learn part of a task and return after difficulty.

Technical mastery, specific self-efficacy and global self-worth nevertheless remain distinguishable. A person can acquire skill while continuing to interpret mistakes as evidence of inadequacy. Shame and self-criticism therefore warrant attention when relevant to the formulation. Compassion-focused therapy provides one example of explicitly addressing these difficulties (Leaviss and Uttley, 2015).

Training offers frequent encounters with being inexperienced. Sequences are forgotten and coordination develops unevenly. A behavioural experiment could examine a prediction that an ordinary mistake will lead to rejection. It requires an agreed prediction, suitable practice and review of what happened, including the participantโ€™s interpretation and protective strategies.

Progression can vary through complexity, speed, effort or social visibility. These dimensions need not increase together. For someone whose worth depends on achievement, a useful task might involve receiving correction without self-attack or stopping at an agreed level.

Assertiveness can also be rehearsed through asking for clarification, requesting lighter contact or declining an additional round. The instructorโ€™s response becomes part of the learning. Physical performance provides only a partial account of progress when the intended change concerns communicating a need or recovering from a mistake.

Manageable challenge and coping rehearsal

Exertion, uncertainty and frustration can provide occasions to practise coping. The first challenge may be entering the venue; later tasks might involve an unfamiliar combination or remaining engaged after an error.

Meichenbaum and Deffenbacherโ€™s (1988) stress inoculation framework offers a useful structure: develop a shared understanding, acquire and rehearse coping skills, then apply and review them in relevant situations. This directs attention to preparation and coping choices before increasing demand.

Brief self-instructions such as โ€œslow the sequenceโ€, โ€œask for clarificationโ€ or โ€œreset and try againโ€ connect language with available actions. Hatzigeorgiadis et al. (2011) found that self-talk interventions improved sport performance. Their wider therapeutic contribution needs assessment against the intended clinical outcome.

Physical endurance, anxiety sensitivity and distress tolerance are distinct. LeBouthillier and Asmundson (2015) found that one aerobic exercise session reduced anxiety sensitivity without improving distress tolerance or intolerance of uncertainty. Their later four-week trial involving 48 participants reported benefits for distress tolerance and intolerance of uncertainty following resistance training (LeBouthillier and Asmundson, 2017). Different activities and doses may influence different processes.

Craske et al. (2014) emphasise expectancy violation and new learning within exposure rather than requiring fear to diminish during a session. Movement could provide a setting for such learning where a relevant fear has been identified. The task might examine whether activation can be experienced while retaining choice. Increased intensity alone is an inadequate measure of therapeutic progress.

Attention, flexibility and personal meaning

Movement sequences require attention to targets, balance, timing and instructions. A participant can notice distraction or self-criticism and return to the next action. This provides a concrete setting for attentional practice, with transfer beyond the task requiring review.

Acceptance and commitment therapy offers language for willingness, defusion and values-guided action. Macri and Rogge (2024) review psychological flexibility and inflexibility processes within ACT. Applied here, willingness might involve allowing embarrassment while trying a chosen task; defusion might involve noticing โ€œeveryone thinks I am uselessโ€ without treating it as an instruction to leave. Flexibility also includes adapting or declining when those choices serve the personโ€™s goals.

Dialectical behaviour therapy distinguishes mindfulness, emotion regulation, distress tolerance and interpersonal effectiveness (Chapman, 2006). These distinctions help specify whether a task concerns attending, modifying activation, enduring distress or communicating a need.

Absorption during training may provide welcome relief. Its function deserves review if movement becomes the only way to avoid painful thoughts. Psychological flexibility concerns the range of responses available, including the ability to rest and engage with difficulties elsewhere.

Meaning should likewise be elicited directly. Practice may represent cooperation, capability or community membership; it may also become organised around punishment or approval. Park (2010) distinguishes efforts to make meaning from meanings actually achieved. Attendance and enjoyment therefore provide incomplete evidence of changes in longstanding beliefs or identity.

Bodily activation, breathing and recovery

Training may make breath-holding, muscular bracing, fatigue and rising arousal more noticeable. A participant can practise adjusting effort, recognising tension and responding to changing demands.

Competition research demonstrates that these demands can be accompanied by substantial physiological activation. Slimani et al. (2018) identified increases in cortisol, adrenaline and noradrenaline following striking combat events compared with pre-combat measurements. These findings concern acute responses to competition and cannot establish how every recreational participant experiences training or whether participation produces lasting improvements in regulation.

Our observations suggest that increasing familiarity may sometimes be accompanied by less unnecessary tension, more economical movement and better-paced effort. We propose that this can provide a setting for learning to act purposefully while activated. This interpretation concerns observable responses; particular hormone or neurotransmitter levels cannot be inferred from performance.

Sometimes the useful task involves reducing unnecessary activation. At other times, it involves discovering that activation is tolerable. Instructions should fit the therapeutic purpose and physical demand.

Breathing during movement differs from a separate paced-breathing practice. Balban et al. (2023) examined brief daily structured breathing protocols, including cyclic sighing, and reported effects on mood and respiratory rate. Fincham et al. (2023) found that coherent breathing at approximately 5.5 breaths per minute did not outperform a matched 12-breaths-per-minute practice on mental health and wellbeing outcomes in 400 participants. These studies concern particular breathing protocols rather than breathing instructions during striking combinations.

During exertion, ventilation must accommodate physical demand. Recovery breathing can be explored separately and reviewed for whether it supports participation. A practice may become restrictive if the person concludes that discomfort must disappear before action is possible.

Recovery also concerns how a session ends, rest between training days and responses to fatigue. These observations help establish whether exercise supports wider functioning or becomes punitive. Recovery should remain adaptable rather than become another performance standard.

Belonging, coaching and interpersonal boundaries

A supportive club can offer repeated contact around shared activity. Connection may develop without immediate personal disclosure. Predictable routines, recognition and constructive feedback may make participation easier, depending on the interpersonal environment.

For people with histories of coercion or interpersonal threat, proximity, commands, touch or unpredictability may carry particular significance. Preparation should establish what participation involves, available adaptations and how consent can be withdrawn. An instructor who respects a request can support learning that needs may be expressed without rejection.

A first step may involve contacting an instructor, observing a class or trying a short introduction. Review should address experience and interpretation. Did the anticipated difficulty occur? Did assistance feel useful or become further evidence of inadequacy? Was there interest or enjoyment?

An unpleasant experience may justify another setting. It should not automatically be interpreted as avoidance to overcome. The suitability of the environment remains part of the formulation.

A hypothetical clinical illustration

The following illustration describes proposed professional reasoning rather than an actual patient account.

An adult interested in boxing avoids asking for help at work and expects that expressing a need will provoke irritation. They also stop unfamiliar activities after mistakes, interpreting difficulty as evidence of incompetence. Assessment explores physical health, previous learning experiences, the meaning of bodily activation and whether current relationships contain actual hostility. It identifies strengths, including an interest in technical skills and previous occasions of effective communication.

A shared hypothesis is that remaining silent provides immediate relief while preventing learning about how others respond to reasonable requests. The client chooses a short non-contact introduction with an instructor who welcomes adaptation. The proposed experiment concerns requesting a slower pace during a manageable combination.

Before practice, clinician and client specify the prediction and rehearse a credible request. Afterwards, review examines whether the request was made, how the instructor responded and how that response was interpreted. If a respectful response is dismissed as โ€œonly because this is therapyโ€, the interpretation becomes a question to investigate. A dismissive response would require reconsideration of both the prediction and the suitability of the setting.

An agreed experiment outside training might involve asking a colleague to clarify an instruction. Review would distinguish willingness, actual behaviour and confidence, which may change at different rates. The example shows how a chosen physical activity can provide a setting for testing a prediction and rehearsing agency.

Evaluating learning beyond training

Evaluation should match the formulation. Technical competence, specific self-efficacy, global self-worth, self-critical responding and everyday participation are related but distinct outcomes. Session review can record predictions, coping choices, interpretation and actual behaviour. Suitable symptom or wellbeing measures can complement personally meaningful goals.

Learning outside training requires further opportunities for practice. Someone who returns to a drill after an error might revisit an activity they previously abandoned. A participant who communicates a limit may examine where else expressing a preference matters. These are further experiments with outcomes to review.

Follow-up should examine whether changes persist, whether participation continues and what happens during interruptions. Attendance, adaptations, adverse experiences and discontinuation provide information about fit. Missed sessions and fluctuating energy should be anticipated within a realistic routine.

The clientโ€™s explanation should remain distinguishable from the clinicianโ€™s inference. Reported improvement is valuable information, while causal conclusions require stronger evidence.

Physical risk and professional responsibilities

Contact combat sports introduce injury exposures requiring explicit consideration. Head impacts and concussion are material concerns; the Association of Ringside Physicians has emphasised the particular demands of concussion management in this setting (Neidecker et al., 2019).

Non-contact practice can provide movement and learning opportunities without making head contact part of the therapeutic task, but it is not injury-free. Grappling, kicking and pad work place demands on joints, balance and physical capacity.

Selection and progression should account for health, previous injury and current capacity, with appropriate professional input where needed. Participation should permit stopping and distinguish ordinary effort from pain or symptoms requiring reassessment.

Psychotherapy and martial arts instruction require separate competencies. A clinician using physical tasks needs relevant competence and suitable arrangements, or collaboration with a qualified instructor. Clear roles, informed consent, confidentiality and agreed communication help participants understand what is offered.

Combining roles requires attention to whether the person feels free to disagree or stop. Information shared with an instructor should be limited to what is needed for agreed coordination and shared with the clientโ€™s consent.

Limitations and research priorities

This selective review combines heterogeneous exercise findings, discipline-specific research and conceptual accounts. Its source selection may omit relevant evidence, and it provides no pooled estimate or formal appraisal of the literature as a whole. Observations and individual experiences inform the clinical proposal but do not establish treatment effectiveness.

Smith and Merwin (2021) describe interacting biological and behavioural pathways through which exercise may influence mental health. General findings concerning cognition, inflammation or neuroplasticity cannot establish that a particular martial arts programme produces the same changes or that those changes explain clinical improvement.

A useful comparative question is whether explicit formulation-guided instruction adds benefit to otherwise similar physical practice. Research could compare matched programmes with and without agreed psychological tasks, accounting for encouragement, contact time, progression and expectations. Comparisons with other meaningful activities could examine shared contributions such as mastery and social connection.

Individualisation also deserves study. Does matching preferences and therapeutic goals improve engagement? Which features of instruction influence participation? When should the initial choice be revised?

Prospective assessment should measure intended outcomes and candidate processes over time. Changes in proposed mechanisms should precede the outcomes they are intended to explain, with alternative explanations considered.

Carefully planned single-case experimental designs may help investigate delivery before larger trials. Follow-up, concurrent care, practitioner competence and less favourable experiences should be reported. Including people who discontinue or find the activity unsuitable would improve understanding of practical limits.

Conclusion

The available evidence suggests that martial arts training can support mental health for some participants, although benefits vary across practices, populations and training environments. Its place within individualised care depends on what participation offers the particular person.

Martial arts bring physical activity, technical learning and interpersonal exchange together, creating opportunities to practise choice during manageable challenge. Therapeutic goals may concern developing confidence, responding differently to mistakes, communicating limits, coping with activation or reconnecting with others. Clinical usefulness depends on matching these opportunities to the personโ€™s formulation and reviewing what becomes available beyond training.

The wider exercise literature supports therapeutic relevance, while the specific outcomes and mechanisms of martial arts require further investigation. Our observations inform a clinical proposal: chosen and appropriately adapted practice may provide a setting in which people test expectations, develop agency and participate more fully in a life they value.

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About the Authors

Daniel Mirea is the founder of NeuroAffective-CBT, an accredited CBT therapist and a university lecturer. He is also a trained martial artist and a sports-psychotherapy consultant.

Chris People holds a black belt in traditional Japanese martial arts and teaching awards in combat sports and Brazilian martial arts. He trains both adults and children and is an accredited Hypno-CBT therapist and trainer. He is also undertaking training in psychotherapy.

Declaration of Interests and Article Scope

Daniel Mirea founded NeuroAffective-CBT, which provides a conceptual perspective discussed in this article. The clinical proposals draw partly on the authorsโ€™ observations and personal experiences of training. No original patient data are reported, and the clinical illustration is hypothetical.

The NeuroAffective-CBT Formulation of Pain: Understanding the Bodyโ€“Brainโ€“Affect Connection

Daniel Mirea (June, 2026)
|The NeuroAffective-CBTยฎ Journal |ย 

Pain is not simply a signal travelling from the body to the brain. It is a neuroaffective experience emerging from the continuous interaction between physiology, emotion, cognition, and context.

Abstract

Pain has traditionally been conceptualised as a direct consequence of tissue damage, whereby nociceptive signals travel from the body to the brain and are subsequently perceived as pain. However, contemporary neuroscience suggests that this explanation is incomplete. Modern pain science increasingly recognises pain as a multidimensional neurobiological and psychological experience that emerges from the continuous interaction between sensory information, emotional states, memory, learning, expectation, context, and prediction. This article explores the distinction between nociception and pain, reviews the role of spinal gating and descending modulation pathways, and examines how affective and cognitive processes contribute to the conscious experience of pain. Drawing upon developments in affective neuroscience, cognitive neuroscience, and contemporary pain research, the article proposes that pain is best understood as a neuroaffective phenomenon rather than a simple sensory event. A NeuroAffective-CBTยฎ (NA-CBTยฎ) perspective is presented, conceptualising pain as the product of an ongoing interaction between the body, brain, and affective systems. Understanding pain through this integrative framework may help clinicians and individuals alike appreciate why pain can persist in the absence of ongoing tissue damage and why effective treatment often requires a biopsychosocial and neuroaffective approach.

Keywords: Pain, Nociception, NeuroAffective-CBTยฎ, Chronic Pain, Affective Neuroscience, Central Sensitisation, Predictive Processing, Pain Perception, Cognitive Behavioural Therapy, Neuroaffective Formulation


The Traditional View of Pain

Although pain has been extensively studied within medicine, neuroscience, and rehabilitation disciplines, discussions within psychotherapy have often focused primarily on symptom management rather than on understanding pain as a complex neuroaffective experience. From a NeuroAffective-CBT perspective, this distinction is important because many of the emotional difficulties presented in therapy involve physiological distress that is experienced, interpreted, and responded to in ways that closely resemble the mechanisms observed in pain itself.

Therefore, pain is not simply something we detect. It is something we experience. And experiences emerge from the continuous conversation between the body, the brain, and affect.

Most of us have been taught a relatively simple explanation of pain. You step on a nail. The injured tissue sends a pain signal through the nerves. The signal travels up the spinal cord.

The brain receives the message. You feel pain.

Simple. Logical. Intuitive.

And yet, although this explanation contains some truth, it is only part of the story.

Over the last several decades, advances in neuroscience, psychology, pain medicine, and affective neuroscience have fundamentally changed our understanding of pain. What we once believed to be a straightforward sensory process is now understood to be a far more complex interaction between the body, brain, emotions, memories, beliefs, expectations, and context.

In many ways, pain provides one of the clearest examples of how the body, brain, and affective systems continuously interact to shape our lived experience.

Most educational diagrams describe pain as a four-step process:

1. Detection of Potential Harm

Specialised nerve endings known as nociceptors detect potentially harmful stimuli such as:

  • Extreme heat
  • Excessive pressure
  • Tissue injury
  • Chemical irritation

These receptors are often described as “pain receptors,” although this is not entirely accurate.

Their actual role is to detect potential danger.

When activated, they send electrical signals through peripheral nerves toward the spinal cord.

2. The Spinal Gate

The signal reaches the spinal cord, where information is filtered before continuing toward the brain.

This concept originates from the famous Gate Control Theory of Pain, proposed by Ronald Melzack and Patrick Wall in 1965.

According to this theory, the spinal cord functions somewhat like a gatekeeper.

Some signals are allowed through. Others are dampened. Others may be amplified.

This explains why rubbing an injured area often reduces discomfort. Touch signals can partially compete with and inhibit nociceptive input at spinal cord level.

3. Modulation

Signals reaching higher centres of the nervous system can be increased or decreased by descending pathways from the brainstem.

In some situations, pain can be dramatically suppressed.

Examples include:

  • Soldiers injured in battle
  • Athletes finishing a race despite serious injuries
  • Emergency situations where survival is prioritised

Conversely, pain can also be amplified by stress, anxiety, fear, sleep deprivation, inflammation, or sensitisation.

4. Conscious Perception

If sufficient information reaches the brain, pain becomes consciously experienced.

This is where most simplified diagrams end.

However, this is also where the most interesting part of the story begins.


The Biggest Misunderstanding About Pain

Perhaps the most important discovery in modern pain science is this:

Pain signals are not actually pain.

The nerves do not carry pain itself.

They carry information.

They carry evidence.

They carry warning signals.

What travels through the nervous system is better described as:

Nociception

Nociception refers to the detection and transmission of potentially harmful stimuli.

Pain, however, is something different.

Pain is an experience.

And experiences are generated by the brain.

This distinction may sound subtle, but it changes everything.


Nociception Without Pain

Consider the following examples.

A footballer breaks a bone during an important match and continues playing.

A soldier is shot in combat and reports little or no pain until reaching safety.

An individual involved in a car accident walks around helping others before realising they are injured.

In all these situations:

The injury exists.

The nociceptive signals exist.

Yet the pain experience is significantly reduced or absent. The nervous system has decided that survival is currently more important than suffering.


Pain Without Injury

Now consider the opposite situation.

An individual experiences severe chronic pain despite normal scans and medical investigations.

Someone develops phantom limb pain after amputation.

A person with fibromyalgia experiences widespread pain despite no obvious tissue damage.

An individual suffers debilitating migraines despite no visible injury.

In these situations, pain exists. Yet tissue damage may be minimal or absent. Again, pain cannot simply be explained as a direct readout of injury.

Something else is happening.


The Brain Is Not Reading Pain

A common misconception is that the brain acts like a computer reading incoming messages. The reality is far more sophisticated.

Modern neuroscience increasingly supports the idea that the brain functions as a prediction machine. Rather than passively waiting for information, the brain continuously asks:

“What is happening?”

“How dangerous is it?”

“What should I do about it?”

Pain appears to emerge from the brain’s attempt to answer these questions.

The human brain rapidly combines incoming sensory information with previous experiences, memory, learning, expectations, emotional state, beliefs, current stress levels, and environmental context before constructing the experience we call pain.

Pain is therefore not merely detected. Pain is actively constructed by the brain based upon incoming information, prior learning, emotional state, and context.


Why Context Matters

Imagine stepping on the same object under different circumstances.

Scenario One:

You are walking barefoot through your garden.

You step on a sharp object unexpectedly.

Pain is immediate.

Scenario Two:

You are undergoing a medical procedure.

You know discomfort is expected.

You trust the clinician.

The same level of stimulation may feel significantly less painful.

Scenario Three:

You are highly anxious, exhausted, sleep deprived, and worried about your health.

The exact same physical stimulus may feel dramatically worse.

The tissue has not changed.

The brain’s interpretation has changed.


The Emotional Brain and Pain

One of the greatest limitations of many pain models is that they largely ignore emotion. Pain is not simply sensory. Pain is profoundly emotional. Several brain regions contribute to the experience.

Somatosensory Cortex

Helps determine (1) Where the pain is (2) How intense it is

Insula

Processes bodily awareness and internal sensations.

Anterior Cingulate Cortex

Contributes to suffering and distress.

Amygdala

Assesses threat and danger.

Generates fear responses.

Prefrontal Cortex

Adds meaning, interpretation, planning, and decision making.

Pain emerges through the interaction of all these systems rather than from a single pain centre.

There is no single location in the brain where pain exists.

Pain is a network phenomenon.


Fear Can Increase Pain

Imagine touching a hot stove.

The immediate pain serves an adaptive purpose.

You withdraw your hand.

Problem solved.

However, if the nervous system begins associating many harmless experiences with danger, pain can become amplified.

The more fearful we become of pain:

  • The more we monitor it
  • The more we anticipate it
  • The more attention we give it

The more significant it can become.

This does not mean the pain is imaginary.

It means the nervous system is becoming increasingly protective.

In many chronic pain conditions, the alarm system becomes overly sensitive.

The danger detector becomes too good at its job.


What Chronic Pain Teaches Us

Acute pain protects us.

Chronic pain often reflects protection that has become excessive.

The nervous system learns.

The brain learns.

The body learns.

Neural pathways become strengthened through repetition.

Eventually the system may begin generating pain responses disproportionate to actual tissue damage.

This process is often referred to as:

  • Central sensitisation
  • Neural amplification
  • Pain sensitisation

The pain remains real.

The suffering remains real.

The underlying mechanisms, however, are different from those involved in acute injury.


A NeuroAffective-CBT Perspective

Within NeuroAffective-CBT, pain can be understood through the interaction between three continuously communicating systems:

Body

The body provides physiological information.

This includes:

  • Injury
  • Inflammation
  • Hormonal changes
  • Sleep quality
  • Nutrition
  • Energy availability
  • Physical conditioning

Brain

The brain interprets incoming information.

It generates predictions based upon:

  • Previous experiences
  • Memory
  • Learning
  • Core beliefs
  • Expectations

Affect

Affective systems shape emotional meaning.

These include:

  • Fear
  • Shame
  • Anxiety
  • Helplessness
  • Anger
  • Grief

Together these systems create the subjective experience we call pain.

Within NeuroAffective-CBT, emotional pain and physical pain are not viewed as entirely separate phenomena. Both involve physiological activation, affective meaning-making, cognitive interpretation, and behavioural responses. Clients frequently describe emotional suffering using physical language: a heavy chest, a knot in the stomach, emotional exhaustion, pressure, tension, emptiness, or feeling broken. Understanding pain therefore provides an important framework for understanding emotional suffering itself.


The Core Principle of NeuroAffective-CBT

The Body influences the Brain.

The Brain influences Affect.

Affect influences Behaviour.

Behaviour influences Physiology.

When any part of this system becomes dysregulated, suffering may emerge.

When all parts of the system are addressed together, healing becomes possible.

Why This Matters Clinically

Understanding pain differently changes how we approach treatment.

Rather than asking only:

“Where is the damage?”

We might also ask:

  • What is the nervous system trying to protect?
  • What role is stress playing?
  • What role is sleep playing?
  • What role is fear playing?
  • What role is emotional suppression playing?
  • What role is avoidance playing?
  • What role is physical deconditioning playing?
  • What role is chronic activation of threat systems playing?

These questions do not invalidate physical explanations.

They expand them.


Pain Is Real, Even When Scans Are Normal

One of the most harmful misconceptions encountered in clinical practice is the belief that normal scans mean symptoms are “all in the mind.”

Nothing could be further from the truth.

Modern neuroscience demonstrates that:

  • Pain is real.
  • The nervous system is real.
  • Brain-based processing is real.
  • Emotional amplification is real.
  • Sensitisation is real.

The absence of visible tissue damage does not invalidate suffering.

It simply means the explanation may be more complex than originally assumed.


The Future of Pain Science

Pain science continues to evolve.

Increasingly, researchers are recognising the importance of integrating:

  • Neuroscience
  • Psychology
  • Physiology
  • Immunology
  • Lifestyle medicine
  • Sleep science
  • Exercise science
  • Nutritional psychiatry
  • Metabolic psychiatry

into a more comprehensive understanding of human suffering.

Pain cannot be fully understood through tissue damage alone.

Nor can it be fully understood through psychology alone.

The future almost certainly lies in integration.

A NeuroAffective-CBT Formulation of Pain

From a NeuroAffective-CBT perspective, pain cannot be fully understood through a purely biomedical model, nor can it be adequately explained through a purely psychological framework. Rather, pain emerges from the dynamic interaction between physiological processes, affective systems, and cognitive interpretation. This perspective is consistent with the NA-CBT Bodyโ€“Brainโ€“Affect Triangle, which proposes that emotional and behavioural experiences arise from the continuous bidirectional communication between bodily states, brain-based processing, and affective meaning-making systems.

Within this framework, the body provides ongoing physiological information regarding injury, inflammation, fatigue, energy availability, sleep quality, nutrition, hormonal changes, and physical conditioning. The brain continuously interprets this information through the lens of prior learning, autobiographical memory, expectations, beliefs, and threat predictions. Simultaneously, affective systems assign emotional meaning to incoming experiences, influencing whether bodily sensations are perceived as manageable, threatening, overwhelming, or catastrophic.

Consequently, pain is not viewed as a simple readout of tissue damage but rather as a neuroaffective experience generated by the interaction of these multiple systems.

The Role of Threat Perception

One of the central assumptions within NA-CBT is that the nervous system is fundamentally organised around safety and survival. The brain continuously evaluates internal and external information to determine the level of threat present in any given situation.

When a stimulus is interpreted as dangerous, the nervous system may increase vigilance, muscular tension, autonomic arousal, and pain sensitivity. Conversely, when safety cues are present, physiological regulation improves, threat responses diminish, and pain intensity may decrease.

Importantly, threat perception is not determined solely by objective reality. It is influenced by previous experiences, trauma histories, attachment experiences, health beliefs, social context, and emotional states.

Two individuals may therefore experience the same physical injury in dramatically different ways depending upon how their nervous systems interpret and respond to the event.

Trauma, Emotional Learning, and Pain Amplification

Traumatic experiences can significantly alter the way the nervous system responds to future threats. Individuals who have experienced chronic adversity, abuse, neglect, medical trauma, bullying, or emotionally invalidating environments may develop heightened sensitivity within threat-detection systems.

Over time, the nervous system may become increasingly efficient at detecting danger, sometimes responding to relatively minor stimuli as though they represent significant threats.

Within the NA-CBT model, unresolved trauma memories may continue to influence present-day physiological and emotional reactions long after the original event has passed. Pain can therefore become linked not only to tissue-based signals but also to fear networks, emotional memories, learned associations, and protective behavioural patterns.

This perspective aligns with contemporary research demonstrating the involvement of the amygdala, anterior cingulate cortex, insula, hippocampus, and prefrontal regions in both pain processing and emotional regulation.

The Influence of Shame and Anxiety

NA-CBT places particular emphasis on the role of shame-based emotional schemas and chronic anxiety in maintaining emotional distress and self-sabotaging patterns.

Shame frequently operates as a hidden amplifier of suffering.

Individuals who carry longstanding beliefs such as:

  • “I am weak.”
  • “I should be coping better.”
  • “There must be something seriously wrong with me.”
  • “Nobody understands what I am going through.”

may experience increased emotional distress alongside physical symptoms.

Similarly, chronic anxiety can maintain heightened physiological arousal, increased muscle tension, sleep disruption, hypervigilance, and persistent monitoring of bodily sensations. These processes may inadvertently reinforce pain pathways and increase the perceived intensity of symptoms.

From a neuroaffective perspective, emotional suffering and physical suffering often become intertwined, creating self-reinforcing cycles that can be difficult to break without targeted intervention.

The Original TED Model: Tired, Exercise, and Diet

A central component of the NeuroAffective-CBT framework is the original TED model, which focuses on three fundamental physiological domains that frequently influence emotional wellbeing, stress tolerance, cognitive functioning, and pain perception:

Tiredness, Exercise, and Diet.

Within NA-CBT, TED is often conceptualised as an individual’s internal physiological coach. Before attempting to understand complex emotional reactions, trauma responses, self-sabotaging behaviours, or chronic distress, clinicians are encouraged to assess the extent to which these three biological domains may be influencing the individual’s current functioning.

Tiredness

Sleep deprivation and chronic fatigue can significantly alter the way the nervous system processes both emotional and physical experiences.

Research consistently demonstrates that insufficient sleep is associated with:

  • Increased pain sensitivity
  • Reduced emotional regulation
  • Heightened threat perception
  • Increased anxiety and irritability
  • Poorer stress tolerance
  • Reduced cognitive flexibility
  • Greater physiological arousal

From a neuroaffective perspective, an exhausted nervous system is often a more reactive nervous system.

Individuals experiencing chronic pain frequently report poor sleep quality, whilst poor sleep itself can increase pain intensity, creating a self-perpetuating cycle of distress and physiological dysregulation.

For this reason, improving sleep and recovery is often considered a foundational intervention within the NA-CBT model before attempting more intensive emotional processing work.

Exercise

Physical activity plays a critical role in both emotional and physiological regulation.

Regular movement influences multiple systems associated with pain modulation, including:

  • Endorphin release
  • Stress regulation
  • Neuroplasticity
  • Cardiovascular health
  • Inflammatory processes
  • Mood regulation
  • Self-efficacy and resilience

Importantly, exercise may also help challenge fear-avoidance patterns commonly observed in chronic pain conditions.

Many individuals gradually reduce activity levels because movement becomes associated with discomfort or fear of injury. Whilst avoidance may provide short-term relief, prolonged inactivity can contribute to deconditioning, increased vulnerability, reduced confidence, and further sensitisation of the nervous system.

Within NA-CBT, exercise is therefore viewed not simply as a physical intervention but also as a psychological and neurobiological regulator capable of influencing both mood and pain perception.

Diet

Nutrition provides the biological foundation upon which the brain and body operate.

Emerging evidence from nutritional psychiatry, metabolic psychiatry, and neuroscience increasingly suggests that dietary factors may influence emotional wellbeing, inflammation, energy production, cognitive functioning, and stress resilience.

Poor nutritional habits may contribute to:

  • Fatigue
  • Metabolic dysfunction
  • Increased inflammation
  • Blood sugar instability
  • Reduced concentration
  • Mood fluctuations
  • Poor recovery capacity

From an NA-CBT perspective, diet is not viewed through a restrictive or purely weight-focused lens. Rather, it is considered a crucial component of physiological regulation that may influence how effectively the nervous system responds to both emotional and physical stressors.

TED and Pain Perception

The relevance of the TED model to pain becomes increasingly apparent when viewed through a neuroaffective lens.

An individual who is:

  • Chronically sleep deprived,
  • Physically deconditioned,
  • Nutritionally dysregulated,

may experience a nervous system that is more reactive, more vigilant, and more sensitive to both internal and external stressors.

Consequently, pain intensity may increase even when tissue damage remains unchanged.

Conversely, improvements in sleep, physical conditioning, and nutritional stability may help reduce physiological stress, improve emotional regulation, increase resilience, and support healthier pain modulation pathways.

Within the NeuroAffective-CBT framework, TED therefore represents far more than a lifestyle intervention.

It represents a foundational physiological platform upon which emotional regulation, cognitive flexibility, behavioural change, trauma processing, and recovery can occur.

When individuals begin addressing tiredness, exercise, and diet simultaneously, they are often not simply improving their physical health. They are creating the biological conditions necessary for the nervous system to feel safer, more regulated, and less protective.

From this perspective, the TED model becomes directly relevant to understanding why some individuals remain trapped within cycles of chronic pain, emotional distress, and physiological dysregulation, whilst others gradually move towards recovery and resilience.

Metabolic Health, Ketogenic Therapies and Pain

Over recent years, growing attention has been directed towards the relationship between metabolic health, inflammation, brain function, emotional wellbeing, and chronic illness. Whilst traditionally associated with weight management or epilepsy treatment, ketogenic therapies are increasingly being investigated for their potential effects on neurological, psychiatric, and inflammatory conditions.

As discussed in a recent NeuroAffective-CBT article exploring ketogenic therapies and mental health, emerging research suggests that metabolic dysfunction may influence psychological wellbeing through mechanisms involving inflammation, mitochondrial function, oxidative stress, insulin resistance, and energy metabolism within the brain.

This perspective aligns closely with one of the central assumptions of the NA-CBT model: the brain does not function independently from the body. Physiological dysregulation may influence emotional wellbeing, whilst emotional distress may simultaneously influence physiological functioning.

The relevance of this emerging field to pain should not be underestimated.

Many chronic pain conditions are now recognised to involve not only structural or tissue-based factors but also inflammatory processes, autonomic dysregulation, altered stress responses, sleep disturbance, and changes in central nervous system functioning. Increasingly, researchers are exploring whether metabolic interventions may influence some of these mechanisms.

As stated in the recent NeuroAffective-CBT review of ketogenic therapies:

“The question is not whether ketogenic therapies represent a miracle cure. The question is whether some of the benefits reported by patients may be explained by improvements in physiological regulation, inflammation, energy metabolism, sleep, cognition, and emotional stability.”

This is an important distinction.

Within NA-CBT, ketogenic diets are not conceptualised as psychological treatments. Rather, they may represent one example of how physiological interventions can potentially influence the Bodyโ€“Brainโ€“Affect system.

For some individuals, improvements in metabolic health may be associated with:

  • Reduced systemic inflammation
  • Improved energy regulation
  • Enhanced cognitive clarity
  • Better sleep quality
  • Reduced emotional volatility
  • Improved stress tolerance

All of which may indirectly influence the experience of pain.

Further research is required before definitive conclusions can be reached. However, the growing field of metabolic psychiatry reinforces a principle that sits at the heart of NeuroAffective-CBTยฎ:

The body influences the brain. The brain influences affect. Affect influences behaviour. Behaviour influences physiology.

Understanding pain therefore requires us to look beyond symptoms alone and consider the broader physiological and emotional ecosystem within which those symptoms occur.

Towards an Integrated Understanding of Pain

The clinical implications of this model are significant.

Rather than asking solely:

“Where is the injury?“

NA-CBTยฎ encourages clinicians and individuals to also ask:

  • What is the nervous system trying to protect?
  • What emotional meanings have become attached to the symptoms?
  • What role is fear playing?
  • What role is shame playing?
  • What role is avoidance playing?
  • What role is trauma playing?
  • What role are sleep, nutrition, and physical conditioning playing?
  • What factors are maintaining the brain’s prediction that danger remains present?

These questions do not deny the reality of pain.

Instead, they acknowledge the complexity of human suffering and provide a broader framework for understanding why pain may persist long after tissue healing has occurred.

Ultimately, the NeuroAffective-CBTยฎ model views pain as a whole-person experience emerging from the continuous interaction between the body, brain, and affective systems. By addressing all three domains simultaneously, clinicians may be better positioned to help individuals reduce suffering, improve functioning, and develop a more integrated relationship with their physical and emotional experiences.


Final Thoughts

Perhaps the most important lesson from modern pain science is this:

Pain is not simply a signal travelling from the body to the brain.

Pain is a dynamic neurobiological experience emerging from the continuous interaction between bodily information, emotional states, prior learning, memory, beliefs, context, and prediction.

The body provides information.

The brain evaluates that information.

The affective system gives it meaning.

Together they create the conscious experience we call pain.

Understanding this complexity does not make pain less real.

If anything, it helps explain why pain can sometimes persist long after tissue healing has occurred, why emotions can influence symptoms, why stress can worsen discomfort, and why genuinely effective treatment often requires us to address the whole person rather than a single body part.

In many respects, pain may be one of the clearest demonstrations that human beings cannot be reduced to either mind or body alone.

We are, and always have been, an integrated neuroaffective system.


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Ketogenic Diet and Mental Health

Daniel Mirea (May, 2026)
|The NeuroAffective-CBTยฎ Journal | 

Could Altering Brain Metabolism Improve Emotional Wellbeing?

Abstract

This article explores the emerging fields of metabolic psychiatry and nutritional psychiatry, two rapidly developing areas of research investigating how metabolism, inflammation, insulin resistance, mitochondrial function, and nutrition may influence mental health and brain functioning. It examines the growing interest in ketogenic diets, originally developed in the 1920s as a treatment for epilepsy, as potential interventions capable of affecting mood, cognition, emotional regulation, and psychiatric symptoms through changes in brain energy metabolism.

The article also considers an important conceptual question: why are these developments increasingly discussed within psychiatry and medicine, yet far less frequently within mainstream psychology and psychotherapy? While nutritional psychiatry focuses upon the biological and medical relationship between diet and mental illness, psychological models have historically placed greater emphasis upon cognition, behaviour, trauma, attachment, and emotional learning. Emerging integrative approaches such as NeuroAffective-CBTยฎ (NA-CBTยฎ) attempt to bridge this divide by recognising that psychological functioning and physiological regulation continuously interact within the Bodyโ€“Brainโ€“Affect system.

Although research in this area remains in its early stages, increasing evidence suggests that mental health and metabolic health may be far more interconnected than previously understood.

The relationship between nutrition, metabolism, and mental health is increasingly recognised as one of the most important discussions within modern psychiatry and integrative psychotherapy.

Keywords:
Ketogenic diet; mental health; metabolic psychiatry; nutritional psychiatry; NeuroAffective-CBT; NA-CBT; brain metabolism; insulin resistance; mitochondrial dysfunction; emotional regulation; nutritional ketosis; psychotherapy; metabolism and mental health; inflammation; neuroplasticity; brain energy; metabolic health; depression; anxiety; bipolar disorder; ADHD; trauma; Bodyโ€“Brainโ€“Affect model.

Introduction: Exploring the Emerging Science of Metabolic Psychiatry

For decades, mental health treatment has focused primarily on psychotherapy and medication. These approaches remain incredibly important and, for many people, life-changing. However, a growing body of research is beginning to suggest that another major factor may have been underestimated for far too long:

Metabolic health.

Researchers working within the emerging field of metabolic psychiatry are increasingly exploring how brain energy, inflammation, insulin resistance, diet, and mitochondrial function may influence emotional wellbeing and psychiatric symptoms.

One of the most discussed interventions within this field is the ketogenic diet โ€” not simply as a weight-loss strategy, but as a possible way of improving how the brain produces and uses energy.

At its core, the idea is surprisingly simple:

Mental health and physical metabolism may be far more interconnected than we once believed.


What Is the Ketogenic Diet?

The ketogenic diet was originally developed in the 1920s as a medical treatment for severe epilepsy in children. Physicians had noticed that periods of fasting sometimes dramatically reduced seizures, but prolonged fasting was obviously not sustainable. Researchers therefore attempted to create a diet that could reproduce the metabolic effects of fasting while still allowing people to eat normally.

The result became known as the ketogenic diet.

A ketogenic diet significantly reduces carbohydrates while increasing fat intake and maintaining moderate protein levels. This shifts the body away from relying primarily on glucose (sugar) for energy and toward burning fat and producing molecules called ketones.

This metabolic state is known as nutritional ketosis.

Ketones can act as an alternative fuel source for the brain, and many researchers now believe that this change in fuel supply may affect not only physical health, but also emotional and cognitive functioning.

In simple terms, a ketogenic diet is a low-carbohydrate, moderate-protein, high-fat nutritional approach designed to shift the body away from relying primarily on glucose (sugar) for energy and toward producing ketones as an alternative fuel source. Ketones are molecules produced by the liver through the breakdown of fat and can be used by the brain and body for energy.

In practical terms, ketogenic diets typically encourage foods such as oily fish, eggs, olive oil, avocado, nuts, seeds, natural full-fat dairy products, and unprocessed meats, while reducing foods high in sugar and refined carbohydrates such as sweets, sugary drinks, white bread, pastries, ultra-processed snacks, and heavily processed fast foods. Many clinicians and researchers also emphasise the importance of prioritising healthier fats and minimally processed foods rather than simply consuming large amounts of fat indiscriminately.

Therefore ketogenic diets are not about proteins over everything else. Protein intake on a ketogenic diet is generally calculated according to body weight rather than height. The formula is rather simple:

Protein (g/day) = Body Weight (Kg) ร— 1.2โ€“1.75

Where:

โž” 1.2 g/kg = Sedentary individuals

โž” 1.4โ€“1.6 g/kg = Most adults following a ketogenic diet

โž” 1.75 g/kg = Physically active individuals, older adults, or those seeking to preserve lean muscle mass

Example:

An individual weighing 80 kg would require:

80 kg ร— 1.2 = 96 g protein/day

to

80 kg ร— 1.75 = 140 g protein/day

Therefore, a daily protein intake of approximately 96โ€“140 g of protein would be appropriate.

For individuals who are significantly overweight or obese, protein requirements may be calculated using ideal body weight or estimated lean body mass rather than total body weight.

Importantly, ketogenic diets are not high-protein diets. Therapeutic ketogenic approaches are typically characterised as high-fat, moderate-protein, and very-low-carbohydrate diets, with protein intake maintained at levels sufficient to preserve muscle mass while supporting nutritional ketosis.


The Forgotten Medical History of Keto

Although ketogenic diets have become fashionable in recent years, their origins are deeply medical rather than commercial.

The ketogenic diet was first formally introduced in 1921 at the Mayo Clinic by Dr. Russell Wilder. At the time, it was considered a serious neurological treatment rather than a lifestyle trend.

Throughout the 1920s and 1930s, ketogenic diets were widely used in hospitals to treat epilepsy, often with remarkable results. Interest later declined after anti-seizure medications became available in the 1940s and 1950s, largely because medication was easier to prescribe and commercially scalable.

For decades, ketogenic therapy remained mostly confined to treatment-resistant epilepsy.

Only in the past twenty years has scientific interest expanded again. Researchers are now exploring ketogenic and low-carbohydrate approaches in relation to obesity, insulin resistance, type 2 diabetes, Alzheimerโ€™s disease, Parkinsonโ€™s disease, migraine disorders, inflammation, and increasingly, mental health conditions such as depression, bipolar disorder, schizophrenia, anxiety disorders, and ADHD.

This newer field, more established in the United States than in the United Kingdom, is often referred to as metabolic psychiatry, a field that has emerged more recently than nutritional psychiatry. Using modern neuroscience and advances in brain metabolism research, it is beginning to revisit an old question:

Could changing brain metabolism influence mental health outcomes?


The Brain Is an Energy-Hungry Organ

The human brain represents only around 2% of total body weight, yet it consumes roughly 20% of the bodyโ€™s energy at rest.

In simple terms, the brain is extraordinarily energy-demanding.

Increasingly, researchers suspect that many psychiatric and neurological conditions may involve problems with how the brain produces, accesses, or regulates energy. Scientists are investigating links between mental illness and insulin resistance, inflammation, oxidative stress, mitochondrial dysfunction, and disrupted neurotransmitter regulation.

This has led to an important question:

What happens when the brain is not being fuelled efficiently?

Some researchers now believe that certain psychiatric symptoms may partly reflect a โ€œbrain energy crisisโ€ occurring at the cellular level.


โ€œChanging the Brainโ€™s Operating Systemโ€

Harvard psychiatrist Chris Palmer has described the ketogenic diet as potentially changing the brainโ€™s โ€œoperating system.โ€

When the body moves away from a high-carbohydrate, high-insulin state and begins using ketones for fuel, brain cells appear to function differently. Researchers believe this metabolic shift may influence inflammation, neurotransmitter balance, oxidative stress, hormone regulation, and mitochondrial function.

Some scientists hypothesise that ketones may provide a more stable and efficient fuel source for certain brain cells, potentially improving energy production while reducing inflammatory stress.

Although the science is still evolving, this may help explain why some individuals report improvements not only in weight or energy levels, but also in mood stability, concentration, emotional regulation, and mental clarity.


Mental Health and Metabolic Dysfunction

Modern psychiatry is increasingly recognising that mental health difficulties are not always โ€œjust psychological.โ€

Large studies have repeatedly found strong associations between psychiatric conditions and metabolic problems such as obesity, insulin resistance, metabolic syndrome, inflammation, and type 2 diabetes.

This does not mean that depression, anxiety, bipolar disorder, ADHD, PTSD, or schizophrenia are โ€œcaused by diet.โ€ Mental health is always complex and multi-layered. Trauma, relationships, stress, genetics, attachment history, and social environment all matter enormously.

However, biology matters too.

In fact, poor metabolic health may sometimes worsen emotional regulation, cognitive function, fatigue, motivation, sleep quality, and stress resilience. To complicate matters further, many psychiatric medications themselves can contribute to weight gain, insulin resistance, and metabolic dysfunction.

Whilst much of the emerging ketogenic psychiatry literature has focused upon symptom reduction, an equally important question may be whether metabolic interventions influence a person’s ability to engage with psychotherapy itself. This issue is particularly relevant within NeuroAffective-CBT (NA-CBT), where emotional regulation, cognitive flexibility, behavioural activation, and trauma processing are understood as dependent upon the ongoing interaction between physiology, affect, and cognition within the Bodyโ€“Brainโ€“Affect system.


Ketogenic Diets and Psychotherapy Engagement: A NeuroAffective-CBT Perspective

Recent work by Laurent (2026) has proposed an important conceptual shift in how ketogenic metabolic therapy (KMT) may be understood within mental health services. Rather than focusing solely on whether ketogenic interventions directly reduce psychiatric symptoms, Laurent suggests that an equally important question is whether metabolic stabilisation may improve a person’s capacity to engage with psychotherapy itself.

Writing specifically about Cognitive Behavioural Therapy for Psychosis (CBTp), Laurent highlights that many individuals struggle to fully participate in treatment because of factors such as sleep disturbance, cognitive overload, emotional reactivity, poor concentration, low distress tolerance, fluctuating motivation, and difficulties completing between-session therapeutic tasks. These barriers often interfere with treatment initiation, retention, and successful completion.

As Laurent explains:

“The question of this paper is not whether ketogenic therapies are an effective treatment for schizophrenia spectrum disorders. The question is whether this can improve the ability for these patients to utilise CBTp.“

This distinction is clinically significant because it shifts attention from symptom reduction alone towards the broader issue of therapeutic readiness and engagement. Rather than asking whether ketogenic metabolic therapy directly treats psychosis, Laurent asks whether improvements in physiological functioning may help individuals engage more effectively in the psychological work required for meaningful change.

During discussion of the paper, Laurent further observed:

“Could some of the treatment benefits that people are reporting map onto what patients talk about when they discuss having difficulty using CBT?“

This question closely mirrors one of the central assumptions underpinning NeuroAffective-CBT: that psychological change is influenced not only by what individuals think, but also by the physiological state from which those thoughts emerge. Improvements in sleep quality, energy regulation, metabolic functioning, emotional stability, and cognitive clarity may influence therapeutic outcomes not merely through symptom reduction, but by enhancing a person’s capacity to engage in emotional learning, behavioural change, cognitive restructuring, trauma processing, and the development of an integrated sense of self.

Within NA-CBT, therapeutic progress is not viewed solely as a product of cognitive insight. Psychological functioning is understood as emerging from the continuous interaction between physiological regulation, emotional processing, and cognitive interpretation, as illustrated within the Bodyโ€“Brainโ€“Affect Triangle. From this perspective, interventions that improve physiological stability may indirectly strengthen psychotherapy by creating the conditions necessary for reflective thinking, emotional regulation, behavioural activation, and psychological resilience.

Laurent identifies several domains repeatedly reported within the ketogenic psychiatry literature that are also recognised barriers to successful psychotherapy engagement:

  • Sleep disturbance
  • Cognitive burden and “brain fog”
  • Emotional distress reactivity
  • Mood instability
  • Reduced resilience
  • Functional impairment in everyday life

These domains overlap considerably with those addressed within the original NeuroAffective-CBTยฎ TED model (Tirednessโ€“Exerciseโ€“Diet), where physiological regulation is viewed as a prerequisite for optimal emotional and cognitive functioning.

This observation is particularly noteworthy because the original TED model was developed long before the recent emergence of metabolic psychiatry. TED was originally conceived as a practical psychoeducational framework helping clients understand how tiredness, physical activity, nutrition, and lifestyle behaviours continuously influence emotional regulation, cognitive functioning, decision-making, and psychological resilience. From an NA-CBTยฎ perspective, physiological dysregulation frequently manifests as emotional volatility, cognitive overload, reduced distress tolerance, motivational difficulties, and increased vulnerability to shame-based coping patterns. The emerging ketogenic psychiatry literature may therefore be viewed as supporting a broader principle already embedded within the TED framework: when physiology becomes more stable, emotional regulation improves, cognitive flexibility increases, and psychological change often becomes more accessible.

From an NA-CBT perspective, ketogenic interventions should not be viewed as replacements for psychotherapy. Rather, where clinically appropriate and medically supervised, they may function as adjunctive interventions that enhance readiness for psychological treatment. In other words, metabolic interventions may help prepare the psychological and physiological conditions in which psychotherapy can take root and flourish.

This perspective is consistent with a broader biopsychosocial understanding of mental health. When physiological dysregulation is reduced, individuals often experience improved concentration, greater emotional tolerance, increased motivation, enhanced self-reflective capacity, and greater resilience in the face of distress. These changes may allow them to engage more effectively with cognitive restructuring, behavioural experiments, trauma processing, emotional regulation work, and other psychotherapy interventions.

Future research will be needed to determine the extent to which ketogenic metabolic therapy improves psychotherapy engagement across a range of mental health conditions. Nevertheless, the emerging evidence reinforces an important principle already embedded within the NeuroAffective-CBT framework: sustainable psychological change is often easier to achieve when physiological regulation is addressed alongside emotional and cognitive processes. Put simply, when the body functions more effectively, the mind is often better positioned to learn, adapt, regulate, and heal.

Within the NeuroAffective-CBT Bodyโ€“Brainโ€“Affect Triangle, physiological regulation, emotional experience, and cognitive processing are viewed as continuously interacting components of a single integrated system. Changes in sleep quality, nutrition, inflammation, insulin sensitivity, hormonal balance, physical activity, and energy metabolism do not simply affect the body; they may also influence how emotions are experienced, how meaning is constructed, and how individuals respond to psychological challenges.

From this perspective, ketogenic metabolic therapy represents one example of a broader principle that has long been embedded within the NA-CBT framework: psychological functioning cannot be fully separated from physiological functioning. The way we think, feel, regulate emotions, tolerate distress, and engage in psychotherapy is influenced not only by our beliefs, learning history, and relationships, but also by the biological state of the nervous system from which those experiences emerge.

Consequently, interventions that improve physiological regulation may indirectly enhance emotional resilience, cognitive flexibility, distress tolerance, self-reflective capacity, and therapeutic engagement. From a NeuroAffective-CBT perspective, physiology and psychology are not separate domains competing for explanatory power; rather, they represent different levels of the same interconnected human system. The Bodyโ€“Brainโ€“Affect Triangle therefore provides a framework for understanding how changes in metabolism, sleep, nutrition, physical activity, emotional regulation, cognition, behaviour, and relationships continuously influence one another. In this context, ketogenic metabolic therapy may be viewed not simply as a dietary intervention, but as one potential pathway through which physiological stabilisation may facilitate emotional regulation, psychological growth, and meaningful therapeutic change.


Clinical Implications for NeuroAffective-CBT

As discussed previously in the article TED Series, Part II: Insulin Resistance and Mental Health, insulin resistance may influence far more than blood sugar alone. Emerging evidence suggests it may also contribute to fatigue, emotional instability, cognitive slowing, cravings, depressive symptoms, and motivational collapse.

Within the NeuroAffective-CBT framework, these physiological states are understood as directly influencing the Bodyโ€“Brainโ€“Affect system central to emotional functioning.

From this perspective, ketogenic diets may hold psychotherapeutic relevance because they target metabolic flexibility and glucose regulation. By reducing glucose volatility and lowering insulin demand, ketogenic interventions may help stabilise energy availability within the brain and nervous system.

In everyday clinical terms, this may mean that some individuals feel calmer, clearer, less reactive, more emotionally stable, and more capable of engaging in therapeutic work.

Within NA-CBT, TED interventions (Tiredโ€“Exerciseโ€“Diet) are not presented as rigid dietary rules or wellness ideology. Rather, they are viewed as biologically informed interventions that may improve emotional regulation capacity and psychotherapy responsiveness.

When individuals experience chronic fatigue, emotional dysregulation, shame-driven eating, unstable sleep, poor concentration, or constant cravings, psychotherapy itself may become significantly more difficult because the nervous system remains physiologically overwhelmed.

Chronic physiological dysregulation may also increase vulnerability to shame-based interpretations of failure, weakness, inadequacy, and self-criticism, further reinforcing the maladaptive cycles described within the Pendulum Effect model of NeuroAffective-CBT.

Improving metabolic stability may therefore increase a personโ€™s ability to tolerate emotions, engage in trauma processing, participate in behavioural activation, and benefit from cognitive restructuring.

Importantly, NA-CBT does not present ketogenic diets as a miracle cure or replacement for psychotherapy, psychiatric care, or medication. Rather, the model proposes that psychological functioning and physiological functioning continuously interact.

The brain does not operate separately from the body.

Emotional suffering is often both psychological and physiological at the same time.


Final Thoughts

The ketogenic diet is not a universal solution, and the science surrounding metabolic psychiatry remains in its early stages. Much more high-quality research is still needed, particularly regarding long-term outcomes, individual differences, and the interaction between nutrition, metabolism, psychotherapy, and psychiatric care.

However, one of the most important developments emerging from both metabolic psychiatry and nutritional psychiatry may be the growing recognition that mental health cannot be fully separated from physical health.

What we eat influences how we think, feel, regulate emotion, tolerate stress, and engage with the world around us. Brain metabolism, inflammation, insulin resistance, sleep, trauma, lifestyle, and emotional learning may all interact far more dynamically than traditional models once assumed.

At the same time, these developments raise important questions for psychology and psychotherapy. If nutrition and metabolism can influence mood, cognition, motivation, emotional regulation, and neuroplasticity, then psychological therapies may also benefit from greater integration with physiology and lifestyle medicine.

Approaches such as NeuroAffective-CBT (NA-CBT) attempt to bridge this divide by recognising that the brain does not operate separately from the body, and emotional suffering is often simultaneously psychological, neurological, behavioural, and physiological.

Rather than viewing biology and psychology as competing explanations, emerging integrative models increasingly suggest they may represent different levels of the same human system.

The future of mental health treatment may therefore lie not in choosing between biology or psychology, but in understanding how physiology, emotion, cognition, behaviour, relationships, trauma, and meaning continuously interact within one integrated human system. From a NeuroAffective-CBT perspective, lasting psychological change becomes most achievable when the Body, Brain, and Affect are understood not as separate domains, but as interconnected components of the same human experience.


Disclaimer

This article is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Ketogenic diets and therapeutic nutritional ketosis may significantly affect metabolism, medications, blood sugar, blood pressure, and psychiatric symptoms. Individuals considering significant dietary changes, particularly those with mental health conditions, eating disorders, diabetes, or those taking medication, should consult appropriately qualified healthcare professionals before making changes to diet or treatment plans.


References

Chris Palmer (2022). Brain Energy: A Revolutionary Breakthrough in Understanding Mental Health โ€” and Improving Treatment for Anxiety, Depression, OCD, PTSD, and More. BenBella Books.

Georgia Ede (2024). Change Your Diet, Change Your Mind. London: Hodder & Stoughton.

Laurent, N. (2026) ‘Ketogenic metabolic therapy as a candidate adjunct for CBTp delivery in schizophrenia spectrum disorders’, Frontiers in Psychology, 17, 1775511. doi:10.3389/fpsyg.2026.1775511.

Mirea, D. (2025) TED in NeuroAffective-CBTยฎ: An applied self-regulation framework for enhancing emotional well-being through sleep, movement and nutrition. NeuroAffective-CBTยฎ. Available at: https://neuroaffectivecbt.com/2025/12/10/ted-in-neuroaffective-cbt-an-applied-self-regulation-framework-for-enhancing-emotional-well-being-through-sleep-movement-and-nutrition/ (Accessed: 2026).

Russell Wilder (1921). Original work introducing the ketogenic diet as a treatment for epilepsy at the Mayo Clinic.

Further Reading

Articles exploring NeuroAffective-CBTยฎ, emotional regulation, trauma, neuroplasticity, and the Bodyโ€“Brainโ€“Affect model. And additional perspectives integrating physiology and psychotherapy can be found at NeuroAffective-CBTยฎ Articles including: TED Series, Part II: Insulin Resistance and Mental Health

Research literature within Metabolic Psychiatry exploring the relationship between brain energy metabolism, insulin resistance, inflammation, and psychiatric disorders.

Mitochondrial Psychiatry literature investigating the role of mitochondrial dysfunction in depression, bipolar disorder, schizophrenia, and neurodegenerative conditions.

Research into insulin resistance and mental health increasingly suggests associations between impaired glucose metabolism, inflammation, depression, cognitive dysfunction, and emotional dysregulation.

Studies investigating ketogenic therapy in epilepsy continue to demonstrate the long-established neurological effects of nutritional ketosis, particularly in treatment-resistant epilepsy.

Evidence supporting ketogenic diet as an adjunct therapy in the treatment for chronic mental illness: 

MetabolicMind.org

Frontiers | Ketogenic metabolic therapy as a candidate adjunct for CBTp delivery in schizophrenia spectrum disorders