Beyond โ€˜Fake It Till You Make Itโ€™: The Pendulum-Effect, Embodied Rehearsal and the Development of the Integrated-Self

Daniel Mirea (September, 2026)
| The NeuroAffective-CBTยฎ Journal | 

Central proposition: We do not always need to feel confident before acting courageously. Carefully graded action can provide an embodied rehearsal through which affect tolerance, agency and self-trust may gradually develop.

She Knew What She Wanted to Say

Anna had prepared for the meeting more thoroughly than anyone else in the room.

She had read the papers twice, highlighted the relevant figures and anticipated several questions her colleagues might ask. The night before, she had rehearsed different versions of what she wanted to say. By the time the meeting began, there was little about the subject that she did not understand.

Yet when the opportunity to contribute arrived, Anna remained silent.

She felt the change in her body before she could put it into words. Her chest tightened, her throat seemed to narrow and her shoulders became rigid. While another colleague was speaking, Anna stopped listening fully and began monitoring herself.

When should I come in? What if I misunderstand the question? What if they realise that I am not as capable as they think?

She waited for the moment when she would feel certain enough to speak. It did not come.

When a colleague made a point similar to the one Anna had prepared, she nodded in agreement and told herself that there was no longer any reason to contribute. For a few seconds, she felt relieved. The danger of being exposed had passed.

The relief did not last. After the meeting, Anna replayed the conversation, criticised herself for remaining silent and treated the incident as evidence about her identity. She was no longer thinking, I found it difficult to speak in that meeting. She was thinking, I am weak. I am inadequate. This is who I am.

Her response was to prepare even more intensely for the next meeting.

Annaโ€™s colleagues would probably have described her as conscientious, capable and exceptionally well prepared. They would not have seen the cycle beneath her competence: the attempt to overcome self-doubt through perfectionism, the withdrawal when certainty remained impossible and the self-attack that followed.

These responses were understandable in the context of Annaโ€™s history. She had learned early that approval followed achievement and that mistakes attracted criticism. Careful preparation had helped her succeed; monitoring other people had helped her detect changes in mood; silence had sometimes protected her from humiliation. The difficulty was that these strategies had become so thoroughly rehearsed that they felt less like strategies and more like aspects of her personality.

When Anna entered therapy, she said that she wanted to become more confident. What she meant was that she wanted the anxiety to disappear before she acted. She imagined that confident people spoke because they felt certain, while she remained silent because something essential was missing within her.

Her first therapeutic experiment was deliberately modest. She was not asked to dominate a meeting, deliver a flawless presentation or behave as though she felt no anxiety. She was asked to prepare one genuine question and raise it within the first ten minutes.

Before rehearsing the question, Anna noticed what happened when she imagined herself speaking: her shoulders lifted, her jaw tightened and she felt an urge to delay. Rather than treating these reactions as proof that she should remain silent, she practised orienting towards the room, feeling the support of the chair and allowing a slower exhalation.

She then rehearsed the question aloud. At first, her voice was quiet and apologetic, and she prefaced the question with several explanations designed to protect her from being wrong. Gradually, she experimented with saying the same words more simply. She was not pretending to be another person. She was using her own voice to practise a response that her established protective system rarely permitted.

At the next meeting, Annaโ€™s chest tightened again. The familiar prediction returned: Wait until you are completely certain.

This time, she asked the question.

She did not experience a sudden transformation. She did not feel fearless and nobody applauded. The question was answered and the meeting continued.

That ordinary continuation mattered. Anna had spoken while feeling activated. Nobody responded with contempt. Her body mobilised and then began to recover. Her specific prediction of humiliation had not occurred, but neither had she proved that criticism would never happen. She had learned something more credible: uncertainty did not make participation impossible.

This was not โ€˜faking itโ€™. The anxiety was real, the bodily activation was real and the old prediction was still present. The action was also real.

Perhaps the more useful instruction is therefore:

Do not fake the feeling. Practise the action, remain connected to the body, observe what happens and allow the experience to revise what seems possible.

Annaโ€™s experience will accompany the ideas that follow. Her movement between perfectionistic overpreparation, avoidance and self-attack illustrates the Pendulum-Effect Formulation. Her use of voice, posture, attention and action shows why rehearsal is more than positive thinking. Most importantly, her increasing ability to participate while remaining connected to her experience demonstrates how an unfamiliar response may gradually become available within the Integrated-Self.

From Pretence to Rehearsal

The phrase โ€˜fake it till you make itโ€™ is memorable because it reverses a common assumption: that an internal state must arrive before action becomes possible. When I feel confident, I will speak. When my anxiety disappears, I will travel. When I believe I am worthy, I will allow myself to be visible.

Waiting for the preferred feeling can, however, become part of the avoidance cycle. The person receives little corrective information, the feared situation remains unfamiliar and the old self-concept is repeatedly confirmed.

The alternative is not dishonesty. A person can acknowledge, โ€˜I feel anxious and part of me expects rejectionโ€™, while also practising one behaviour associated with agency: making eye contact, expressing a preference, asking a question or remaining present long enough to discover what happens. Confidence may be incomplete, but the action is genuine.

This distinction matters clinically. Pretence requires the person to deny or conceal their experience. Rehearsal asks them to remain in contact with that experience while trying a response that has previously been inhibited. It is not a demand to feel differently on command; it is an opportunity to discover whether feeling anxious, ashamed or uncertain necessarily determines what happens next.

Why Embodiment Still Matters

Some traditional psychological language implies a one-way sequence in which thought creates emotion and the body merely displays the result. Embodied and grounded approaches complicate this picture. Cognitive and affective processes draw upon perception, movement, interoception and situated interaction with the environment. Bodily activity therefore participates in experience rather than serving only as its outward consequence (Barsalou, 2008; Niedenthal, 2007).

Annaโ€™s bodily activation, threat predictions, shame, narrowed attention and silence formed an interacting state. Her tightening chest did not simply report a conclusion her mind had already reached; it contributed to an experience in which participation felt dangerous and withdrawal felt protective.

This does not mean that changing posture automatically transforms identity, or that imagination, performance and lived reality are neurologically interchangeable. Bodily manipulations can influence emotional experience, but their effects may be small, variable and dependent upon context. Research on facial feedback provides a useful warning: the overall effect appears detectable but modest, and outcomes differ according to the task and the emotional experience being measured (Coles, Larsen and Lench, 2019; Coles et al., 2022).

Embodied rehearsal makes a more limited and clinically useful claim. When a person rehearses a boundary or asks a question aloud, the intervention involves more than substituting one thought for another. The person must use their actual voice, regulate breath and muscular activation, direct attention outwards, tolerate the affect evoked by being visible and recover afterwards. The body is neither a shortcut nor a programmable prop; it is part of the situation in which new action and learning become possible.

Acting as Rehearsal Rather Than Pretence

Theatre makes the embodied nature of psychological experience unusually visible. An actor does not learn a role through abstract interpretation alone. The role is organised repeatedly through voice, breath, posture, timing, movement, attention, relationships and responses to the environment. Through rehearsal, the actor temporarily inhabits a behavioural and affective configuration that may initially feel unfamiliar.

Lev Vygotsky recognised that acting raises a psychologically important question: must actors genuinely experience the emotions they portray, or can emotion emerge through the organisation of performance? Discussing Stanislavskiโ€™s system and Diderotโ€™s โ€˜paradox of the actorโ€™, Vygotsky situated emotional experience within a wider relationship among role, action, social meaning, theatrical tradition and audience (Vygotsky, 1999; original work published 1932). His analysis cautions against treating performed and lived emotions as either completely separate or neurologically interchangeable.

Within a different clinical tradition, J. L. Moreno placed action, role and enactment at the centre of psychological change (Moreno, 1946, 1947). In psychodrama, clients do not merely describe an experience. They enter a structured dramatic space in which relationships, conflicts, memories and possible responses can be enacted. Role reversal, doubling, mirroring and role training allow previously unavailable perspectives and behavioural positions to be experienced, observed and rehearsed (Cruz et al., 2018; Moreno, 1946).

Moreno proposed that the self emerges through the roles a person develops and performs, describing role as a bridge between psychiatry, psychology and sociology (Moreno, 1946, 1961). Psychological development, from this perspective, does not require the discovery of one fixed and supposedly authentic identity concealed beneath behaviour. It may involve expanding the personโ€™s role repertoire and increasing the capacity to respond spontaneously and creatively rather than remaining confined within rigid, overlearned patterns (Moreno, 1947, 1955).

A new role does not require a person to become somebody else. It may provide temporary access to an inhibited aspect of their existing repertoire. Someone organised around compliance may rehearse setting a boundary. Someone governed by shame may practise being visible. Someone who anticipates helplessness may experiment with acting from a position of agency.

What initially feels artificial may feel unfamiliar precisely because it contradicts an established protective pattern. A person who has spent years accommodating others may experience an ordinary boundary as unnatural. Someone accustomed to silence may describe speaking with authority as โ€˜not feeling like meโ€™. Yet familiarity is not the same as authenticity. Sometimes what feels most familiar is simply what has been rehearsed for the longest.

Morenoโ€™s concept of surplus reality is relevant here. The psychodramatic space allows a person to enact what did not happen, what has not yet happened or what could not safely be expressed in everyday life (Moreno, 1965). A boundary may finally be spoken or a more agentic position temporarily inhabited. The enactment is not equivalent to lived reality, but it may provide an experiential bridge between what the person currently predicts and what they may gradually become able to tolerate and perform.

Contemporary drama-based interventions employ related processes, including role, narrative, enactment, distancing and witnessed performance. Reviews report promising findings across psychosocial, emotional and behavioural outcomes, while also identifying considerable variation in populations, interventions, methods and study quality (Berghs et al., 2022; Jiang et al., 2023). These findings support careful clinical exploration; they do not establish that performance reliably installs safety, autonomy or a new identity within the nervous system.

From Psychodrama to Behavioural Rehearsal

Moreno was not the only early clinician to place action before emotional readiness. In Conditioned Reflex Therapy, Andrew Salter argued that change could be facilitated through deliberate practice of expressive and assertive behaviour, including speaking directly about feelings, using the first-person pronoun โ€˜Iโ€™, expressing disagreement and accepting praise (Salter, 1949). People were not expected to wait until they felt naturally assertive; behaviour was practised first, including beyond the consulting room, so that experience and interpersonal feedback could begin to modify established patterns.

Salterโ€™s learning-based approach was theoretically distinct from Morenoโ€™s emphasis on role, encounter and dramatic enactment, but both challenged the assumption that insight, confidence or emotional readiness must precede behaviour. Salter explained change through Pavlovian concepts of cortical excitation and inhibition; these ideas are historically important but are not established mechanisms within contemporary neuroscience.

Vygotsky, Moreno and Salter therefore provide different perspectives that can be brought into dialogue with a NeuroAffective-CBTยฎ (NA-CBT) account of embodied rehearsal. They do not validate NA-CBT or establish its mechanisms. They help situate its central proposition within a longer history of understanding action, role and experience as mutually influential.

The Pendulum Beneath the Performance

The Pendulum-Effect Formulation identifies the protective pattern that restricts action; embodied rehearsal creates an opportunity to practise a different response; reflection and repetition allow that response gradually to become available within the Integrated-Self.

Figure 1. The Pendulum-Effect Formulation: Overcompensation, Avoidance and Capitulation represent different protective positions organised around a shared shame-based prediction. Embodied rehearsal, graded action, reflection and repetition provide an alternative agentic pathway through which a different response may gradually become available within the Integrated-Self.

In anticipation of shame, Anna moved towards Overcompensation: preparing excessively, mentally rehearsing every sentence and attempting to eliminate the possibility of error. When complete certainty remained unattainable, she shifted towards Avoidance: delaying her contribution, weakening what she wanted to say or remaining silent. After the meeting, she moved into Capitulation: attacking herself and treating her silence as proof that she was weak or incapable.

These apparently contradictory responses belonged to the same protective system. Overcompensation attempted to disprove the shame-based narrative. Avoidance prevented its anticipated exposure. Capitulation surrendered to it as though it were established fact. Each position offered some immediate regulation or certainty, but their repeated enactment maintained the shame-based understanding of the self.

The pendulum was expressed through the whole person. Overcompensation appeared as urgency, muscular tension, relentless preparation and vigilant monitoring of others. Avoidance appeared as restricted movement, a quieter voice, averted gaze and silence. Capitulation appeared as heaviness, reduced agency and repetitive self-attacking language. Thought, affect, attention, bodily organisation and behaviour reinforced one another.

Anna was not asked to argue her shame away or persuade herself that she was unquestionably competent. Instead, she was invited to test whether the internalised shame-based account represented the whole truth:

If the belief that I am inadequate were not allowed to make the entire decision, what would I do next?

If shame and self-doubt did not have the final say, what would I choose to do next?

These questions are consistent with Greenberger and Padeskyโ€™s use of acting as if, in which a person behaves experimentally in accordance with a more balanced alternative belief and observes the consequences (Greenberger and Padesky, 2016). Anna was not required to believe the alternative in advance; the action created an opportunity to gather information that her established shame-based belief and protective responses had previously restricted.

Asking one genuine question created a position that was neither overcompensating, avoidant nor capitulating. Anna participated without performing perfection. Her anxiety remained present, but it no longer determined the whole response.

In this application, acting as if did not require Anna to suppress her shame or convince herself that she was already confident, lovable or worthy. By enacting a valued response while shame remained activeโ€”and discovering that she could be visible, remain present and recoverโ€”Anna encountered embodied evidence that the shame-based prediction might not represent the whole truth about her. Through reflection and repetition, such experiences can gradually be incorporated into autobiographical identity and become increasingly available within the Integrated-Self.

The broader NA-CBT concept of the Integrated-Self has also been discussed in relation to NeuroAffective Narrative Reconsolidation, where experiences organised around threat and identity-disrupting meaning are revisited in the presence of regulation, agency and new autobiographical meaning (Mirea, 2026). The present article proposes a related, but not identical, process: embodied rehearsal may help the person discover that shame is an affective state accompanied by learned predictions, not an absolute description of identity.

The Pathway from Protective Pattern to Integrated-Self

The movement from a shame-organised protective pattern towards the Integrated-Self can be understood as an iterative sequence rather than a single technique. Although the stages are presented separately, therapy may move back and forth among them as experience generates new information.

1. Recognise the Pendulum movement

The Pendulum-Effect Formulation helps the person recognise how apparently different responses may be organised around the same affective threat. Attention is given not only to behaviour but also to affect, prediction, bodily organisation, attention and relational function.

The question shifts from What is wrong with me? to:

What is this response attempting to prevent, disprove or make certain?

For Anna, extensive preparation was not simply conscientiousness, silence was not simply passivity and self-attack was not simply low mood. Together, they formed a repeating attempt to manage anticipated shame. Overcompensation attempted to disprove inadequacy, avoidance prevented its anticipated exposure and capitulation treated the shame-based account as established fact.

2. Clarify an emerging value

Change requires more than moving away from anxiety or interrupting an unwanted behaviour. The person needs a direction in which they genuinely wish to move: participation, connection, curiosity, honesty, self-respect, courage or appropriate assertiveness.

A value should not become another idealised identity or perfectionistic standard. I want to relate with honesty is more workable than I must become a completely authentic person.

Annaโ€™s emerging direction was participation. Her goal was not to appear impressive, eradicate anxiety or prove that she was competent. It was to contribute something genuine without abandoning herself. This direction provided a reason to act that did not depend upon feeling confident first.

3. Imagine the situation and its difficulties

Present-tense, multisensory imagery can evoke the anticipated situation before the person enters it (Hackmann, Bennett-Levy and Holmes, 2011; Holmes and Mathews, 2010). The image should include the Pendulum impulse, the values-consistent response, uncertain outcomes and recovery. Its purpose is to prepare for reality rather than script compulsory success.

Anna imagined entering the meeting, noticing people turning towards her and feeling the first signs of activation. She became aware of her lifted shoulders, tightened jaw, restricted breathing and urge to delay. She also noticed the familiar prediction: If I speak without complete certainty, I will expose my inadequacy.

The image was not changed into a fantasy in which Anna felt completely calm and everyone responded warmly. Instead, she imagined remaining activated while orienting towards the room, feeling the support of the chair and allowing a slower exhalation. She also imagined several possible outcomes, including interest, indifference, misunderstanding and disagreement.

Imagery made the shame-based prediction observable while creating a provisional model of how Anna might respond differently.

4. Embody and rehearse one observable response

The emerging value is translated into voice, movement, posture, attention and action. The person may rehearse a sentence, question, boundary, request, pause or other form of participation while noticing the protective impulses that arise.

Anna practised asking her question aloud. At first, her voice was quiet and apologetic. She surrounded the question with explanations intended to protect her from being wrong. Through rehearsal, she noticed these movements and experimented with saying the same words more simply.

The purpose was not to manufacture confidence or produce a flawless performance. It was to make participation behaviourally and bodily available. Regulation supported sufficient capacity for learning; it did not require Anna to become completely calm before speaking.

5. Enact it within the therapeutic relationship

Where relevant, the therapy relationship provides an immediate opportunity to practise honesty, disagreement, need, boundary or repair. The consulting room is not merely a protected place in which the person prepares for relationships elsewhere. It is itself a real relationship in which the Pendulum may become visible.

Anna noticed that she also tried to perform competence in therapy. She prepared detailed accounts, searched for the โ€œrightโ€ insight and sometimes agreed with interpretations that did not entirely fit. She worried that disagreement would disappoint the therapist or make her appear resistant.

In imagery and rehearsal, Anna practised telling the therapist that a recent exercise had felt too structured and that she had felt less connected during it. She then expressed this in the session. She remained physiologically activated, but she did not overexplain, withdraw or surrender her experience.

The significance of this moment did not depend solely upon receiving reassurance. Anna discovered that she could express a difference and continue relating. The therapeutic relationship became a real site of embodied rehearsal, feedback and revision rather than another setting in which she had to perform correctly.

6. Test it in everyday life

Rehearsal becomes therapeutically meaningful when it is translated, where safe and appropriate, into graded action. The situation should matter enough to activate the existing prediction but remain sufficiently manageable to permit observation and recovery.

Annaโ€™s first task was deliberately modest: to prepare one genuine question and ask it within the first ten minutes of a meeting. The task activated her fear of exposure without requiring her to dominate the discussion or deliver a flawless presentation.

When the moment arrived, Annaโ€™s chest tightened and the familiar instruction returned: Wait until you are completely certain.

This time, she asked the question. Her anxiety remained present, but it no longer determined the whole response.

7. Reflect, adapt and repeat

The outcome is not classified simply as success or failure. The person compares what was predicted with what occurred, observes how activation changed and considers what supported presence and recovery. Difficult or ambiguous outcomes must be included rather than converted into a compulsory success narrative.

Annaโ€™s question was answered and the meeting continued. She did not experience a sudden transformation, but neither did the humiliation she had predicted occur. Her body mobilised and then began to recover.

Anna had not proved that she would never be criticised. She had learned something more credible: she could speak without complete certainty, tolerate the activation and recover afterwards.

The response was subsequently adapted and tested in other situations. Anna expressed a preference about the direction of a project, declined an additional responsibility and practised contributing without producing an exhaustive defence. Repetition across varied contexts helped make the capacity more accessible without converting it into another rigid rule.

8. Consolidate authorship and expand authenticity

Reflection connects the action with a credible autobiographical understanding of the self. The person is invited to recognise:

A part of me anticipated shame, and I was also capable of acting according to what mattered.

Anna had not merely watched a rehearsed role ask the question. It was her body that tolerated the visibility, her voice that produced the words and her agency that remained present while doubt continued. Consolidating authorship allowed the experience to become part of her developing self-understanding without requiring her to claim permanent transformation.

Within this article, the Integrated-Self refers to an increasingly connected and flexible repertoire in which different affects, needs, values and action tendencies can be acknowledged without one protective position automatically controlling the whole response. Integration does not replace anxiety with permanent confidence or install a new idealised character. It expands what the person can recognise, tolerate, choose and enact.

Annaโ€™s emerging understanding was therefore not:

I am always confident.

It was more credible:

I can notice the urge to prove, hide or surrender and still choose how I want to participate.

Why Action Can Precede Motivation and Confidence

People often wait not only for confidence but also for motivation. Yet motivation is not always a prerequisite for action; it can also be an outcome of action. Behavioural activation, exposure, skills rehearsal and behavioural experiments all make use of the principle that experience can generate information unavailable through reflection alone.

The mechanism is not repetition by itself. Repetition without awareness may consolidate an existing pattern. Useful rehearsal involves a meaningful prediction, tolerable activation, observable action, attention to the outcome, recovery and reflection. If the task overwhelms the person, it may reinforce the expectation that the situation is unmanageable. If it is effortless and emotionally irrelevant, little new learning may occur. Grading is therefore not a concession to weakness but part of the learning design.

Motivation may increase when the person experiences even a small degree of authorship: I did something that mattered while the old feeling was still present. This differs from waiting passively for an internal state to grant permission. It also differs from coercing action in the name of progress. The target must remain personally meaningful, collaboratively chosen and open to revision.

Bringing Embodied Rehearsal into Practice

In practice, embodied rehearsal is developed collaboratively around a personally meaningful and observable response. The therapist and client anticipate how the protective pattern may appear, rehearse the response while allowing manageable activation to remain present and, where appropriate, test it through graded action in everyday life. What was predicted is then compared with what occurred, including how the person responded, recovered and understood their own agency. The process is adapted and repeated across contexts, not to perfect a new performance, but to help a previously inhibited response become increasingly available within the Integrated-Self.

When โ€˜Acting as Ifโ€™ Becomes Harmful

Embodied rehearsal is not universally helpful. It becomes clinically problematic when it asks a person to deny reality, conceal distress or perform beyond their capacity. Several distinctions are essential:

  • Rehearsal versus masking: rehearsal expands choice; masking demands a socially acceptable performance while hiding need, fatigue or neurodivergent difference.
  • Courage versus flooding: graded action permits activation and recovery; flooding overwhelms regulation and may reinforce danger.
  • Aspiration versus deception: practising a skill differs from claiming competence, qualifications or safety that do not exist.
  • Embodiment versus emotional invalidation: posture, breathing or voice work should not be used to tell a distressed person that their feelings are incorrect.
  • Agency versus coercion: the person chooses the target action and retains permission to pause, modify or stop.

Trauma survivors may have extensive experience of performing compliance while internally mobilised, frozen or dissociated. Inviting further performance without attending to consent, relational safety and bodily cues risks repeating the problem. Regulation is not merely a preliminary exercise before the โ€˜realโ€™ intervention; it is part of the conditions under which action can remain chosen and learnable.

A Necessary Scientific Caution

The language of neuroplasticity is sometimes used as though naming it proves a specific intervention. Neuroplasticity is a general property of the nervous system, not evidence that every repeated performance produces therapeutic change. Claims about neurological โ€˜encodingโ€™ require precision: which process was measured, in which population, under what conditions and with what durability?

Performed and lived experiences may overlap in perceptual, motor and affective processes, but they are not interchangeable. Context, consequences, relationships, agency and autobiographical meaning matter. Theatre, psychodrama and role rehearsal may offer bridges to new experience; real-world generalisation still requires testing, reflection and consolidation.

Morenoโ€™s work provides an important clinical and historical foundation for embodied rehearsal, while contemporary research on embodied and grounded cognition offers a partially compatible scientific context. The traditions can be brought into productive dialogue, but Morenian concepts should not retrospectively be presented as neuroscientific discoveries. Their relationship is one of conceptual convergence and clinical compatibility, not proof that contemporary neuroscience has directly validated Morenian theory or NA-CBT.

NA-CBT therefore uses neuroscience to constrain and enrich formulation, not to decorate it. Where evidence is indirect, the language should remain conceptual and provisional.

Rehearseโ€”Do Not Pretend

โ€˜Fake it till you make itโ€™ becomes clinically useful only when pretence is replaced by carefully formulated rehearsal. People do not need to counterfeit confidence or suppress authentic distress. They can practise behaviours that express an emerging value while acknowledging the bodyโ€™s protective response.

The Pendulum-Effect Formulation helps identify how overcompensation, avoidance and capitulation restrict action around a shared affective threat. Embodied rehearsal then gives the person a protected opportunity to use their own voice and body differently. Graded action carries the experiment into lived experience; reflection, recovery and repetition help establish whether the response can become more available across contexts.

Anna did not become somebody else. She did not eliminate uncertainty or install a permanently confident identity. She discovered that the anxious, self-protective part of her did not have to make every decision. Speaking became less foreign, recovery became more familiar and participation became a credible part of what she could do.

From an NA-CBT perspective, the therapeutic question is therefore not, โ€˜How can I convincingly pretend to be someone else?โ€™ It is:

What response needs to be practised so that it can become more available within my Integrated-Self?

References

Barsalou, L.W. (2008) โ€˜Grounded cognitionโ€™, Annual Review of Psychology, 59, pp. 617โ€“645. https://doi.org/10.1146/annurev.psych.59.103006.093639

Berghs, M., Prick, A.J.C., Vissers, C. and van Hooren, S. (2022) โ€˜Drama therapy for children and adolescents with psychosocial problems: a systematic review on effects, means, therapeutic attitude, and supposed mechanisms of changeโ€™, Children, 9(9), 1358. https://doi.org/10.3390/children9091358

Coles, N.A., Larsen, J.T. and Lench, H.C. (2019) โ€˜A meta-analysis of the facial feedback literature: effects of facial feedback on emotional experience are small and variableโ€™, Psychological Bulletin, 145(6), pp. 610โ€“651. https://doi.org/10.1037/bul0000194

Coles, N.A. et al. (2022) โ€˜A multi-lab test of the facial feedback hypothesis by the Many Smiles Collaborationโ€™, Nature Human Behaviour, 6, pp. 1731โ€“1742. https://doi.org/10.1038/s41562-022-01458-9

Cruz, A., Sales, C.M.D., Alves, P. and Moita, G. (2018) โ€˜The core techniques of Morenian psychodrama: a systematic review of the literatureโ€™, Frontiers in Psychology, 9, 1263. https://doi.org/10.3389/fpsyg.2018.01263

Greenberger, D. and Padesky, C.A. (2016) Mind Over Mood: Change How You Feel by Changing the Way You Think. 2nd edn. New York: Guilford Press.

Hackmann, A., Bennett-Levy, J. and Holmes, E.A. (2011) Oxford Guide to Imagery in Cognitive Therapy. Oxford: Oxford University Press. https://doi.org/10.1093/med:psych/9780199234028.001.0001

Holmes, E.A. and Mathews, A. (2010) โ€˜Mental imagery in emotion and emotional disordersโ€™, Clinical Psychology Review, 30(3), pp. 349โ€“362. https://doi.org/10.1016/j.cpr.2010.01.001

Jiang, L., Alizadeh, F. and Cui, W. (2023) โ€˜Effectiveness of drama-based intervention in improving mental health and well-being: a systematic review and meta-analysis during the COVID-19 pandemic and post-pandemic periodโ€™, Healthcare, 11(6), 839. https://doi.org/10.3390/healthcare11060839

Mirea, D. (2026) โ€˜NeuroAffective Narrative Reconsolidation: Integrating Traumatic Memories and the Development of the Integrated-Self in NeuroAffective-CBTโ€™, NeuroAffective-CBT Online Journal, 5 March. Available at: article webpage (Accessed: 3 September 2026)

Moreno, J.L. (1946) Psychodrama: First Volume. Beacon, NY: Beacon House.

Moreno, J.L. (1947) The Theatre of Spontaneity. Beacon, NY: Beacon House.

Moreno, J.L. (1955) โ€˜Theory of spontaneity-creativityโ€™, Sociometry, 18(4), pp. 105โ€“118. https://doi.org/10.2307/2785848

Moreno, J.L. (1961) โ€˜The role concept: a bridge between psychiatry and sociologyโ€™, American Journal of Psychiatry, 118(6), pp. 518โ€“523.

Moreno, J.L. (1965) โ€˜Therapeutic vehicles and the concept of surplus realityโ€™, Group Psychotherapy, 18, pp. 211โ€“216. https://doi.org/10.12926/ek7xhv15

Niedenthal, P.M. (2007) โ€˜Embodying emotionโ€™, Science, 316(5827), pp. 1002โ€“1005. https://doi.org/10.1126/science.1136930

Salter, A. (1949) Conditioned Reflex Therapy. New York: Creative Age Press.

Vygotsky, L.S. (1999) โ€˜On the problem of the psychology of the actorโ€™s creative workโ€™, in Rieber, R.W. (ed.) The Collected Works of L. S. Vygotsky, Volume 6: Scientific Legacy. New York: Kluwer Academic/Plenum, pp. 237โ€“244. (Original work published 1932.)

Authorโ€™s Note

This article presents a conceptual NeuroAffective-CBT formulation intended for professional discussion and psychoeducation. It does not claim that embodied rehearsal is a stand-alone treatment or that the mechanisms proposed here have been uniquely validated for NA-CBT. Interventions should be adapted to individual formulation, consent, clinical risk and professional scope of practice.

Continue reading: Developing Authenticity Through Values-Guided Behavioural Experiments explores the next stage of Annaโ€™s clinical illustrationโ€”from embodied possibility towards values, authorship and authentic living.

The NeuroAffective-CBT Formulation of Pain: Understanding the Bodyโ€“Brainโ€“Affect Connection

Daniel Mirea (June, 2026)
|The NeuroAffective-CBTยฎ Journal |ย 

Pain is not simply a signal travelling from the body to the brain. It is a neuroaffective experience emerging from the continuous interaction between physiology, emotion, cognition, and context.

Abstract

Pain has traditionally been conceptualised as a direct consequence of tissue damage, whereby nociceptive signals travel from the body to the brain and are subsequently perceived as pain. However, contemporary neuroscience suggests that this explanation is incomplete. Modern pain science increasingly recognises pain as a multidimensional neurobiological and psychological experience that emerges from the continuous interaction between sensory information, emotional states, memory, learning, expectation, context, and prediction. This article explores the distinction between nociception and pain, reviews the role of spinal gating and descending modulation pathways, and examines how affective and cognitive processes contribute to the conscious experience of pain. Drawing upon developments in affective neuroscience, cognitive neuroscience, and contemporary pain research, the article proposes that pain is best understood as a neuroaffective phenomenon rather than a simple sensory event. A NeuroAffective-CBTยฎ (NA-CBTยฎ) perspective is presented, conceptualising pain as the product of an ongoing interaction between the body, brain, and affective systems. Understanding pain through this integrative framework may help clinicians and individuals alike appreciate why pain can persist in the absence of ongoing tissue damage and why effective treatment often requires a biopsychosocial and neuroaffective approach.

Keywords: Pain, Nociception, NeuroAffective-CBTยฎ, Chronic Pain, Affective Neuroscience, Central Sensitisation, Predictive Processing, Pain Perception, Cognitive Behavioural Therapy, Neuroaffective Formulation


The Traditional View of Pain

Although pain has been extensively studied within medicine, neuroscience, and rehabilitation disciplines, discussions within psychotherapy have often focused primarily on symptom management rather than on understanding pain as a complex neuroaffective experience. From a NeuroAffective-CBT perspective, this distinction is important because many of the emotional difficulties presented in therapy involve physiological distress that is experienced, interpreted, and responded to in ways that closely resemble the mechanisms observed in pain itself.

Therefore, pain is not simply something we detect. It is something we experience. And experiences emerge from the continuous conversation between the body, the brain, and affect.

Most of us have been taught a relatively simple explanation of pain. You step on a nail. The injured tissue sends a pain signal through the nerves. The signal travels up the spinal cord.

The brain receives the message. You feel pain.

Simple. Logical. Intuitive.

And yet, although this explanation contains some truth, it is only part of the story.

Over the last several decades, advances in neuroscience, psychology, pain medicine, and affective neuroscience have fundamentally changed our understanding of pain. What we once believed to be a straightforward sensory process is now understood to be a far more complex interaction between the body, brain, emotions, memories, beliefs, expectations, and context.

In many ways, pain provides one of the clearest examples of how the body, brain, and affective systems continuously interact to shape our lived experience.

Most educational diagrams describe pain as a four-step process:

1. Detection of Potential Harm

Specialised nerve endings known as nociceptors detect potentially harmful stimuli such as:

  • Extreme heat
  • Excessive pressure
  • Tissue injury
  • Chemical irritation

These receptors are often described as “pain receptors,” although this is not entirely accurate.

Their actual role is to detect potential danger.

When activated, they send electrical signals through peripheral nerves toward the spinal cord.

2. The Spinal Gate

The signal reaches the spinal cord, where information is filtered before continuing toward the brain.

This concept originates from the famous Gate Control Theory of Pain, proposed by Ronald Melzack and Patrick Wall in 1965.

According to this theory, the spinal cord functions somewhat like a gatekeeper.

Some signals are allowed through. Others are dampened. Others may be amplified.

This explains why rubbing an injured area often reduces discomfort. Touch signals can partially compete with and inhibit nociceptive input at spinal cord level.

3. Modulation

Signals reaching higher centres of the nervous system can be increased or decreased by descending pathways from the brainstem.

In some situations, pain can be dramatically suppressed.

Examples include:

  • Soldiers injured in battle
  • Athletes finishing a race despite serious injuries
  • Emergency situations where survival is prioritised

Conversely, pain can also be amplified by stress, anxiety, fear, sleep deprivation, inflammation, or sensitisation.

4. Conscious Perception

If sufficient information reaches the brain, pain becomes consciously experienced.

This is where most simplified diagrams end.

However, this is also where the most interesting part of the story begins.


The Biggest Misunderstanding About Pain

Perhaps the most important discovery in modern pain science is this:

Pain signals are not actually pain.

The nerves do not carry pain itself.

They carry information.

They carry evidence.

They carry warning signals.

What travels through the nervous system is better described as:

Nociception

Nociception refers to the detection and transmission of potentially harmful stimuli.

Pain, however, is something different.

Pain is an experience.

And experiences are generated by the brain.

This distinction may sound subtle, but it changes everything.


Nociception Without Pain

Consider the following examples.

A footballer breaks a bone during an important match and continues playing.

A soldier is shot in combat and reports little or no pain until reaching safety.

An individual involved in a car accident walks around helping others before realising they are injured.

In all these situations:

The injury exists.

The nociceptive signals exist.

Yet the pain experience is significantly reduced or absent. The nervous system has decided that survival is currently more important than suffering.


Pain Without Injury

Now consider the opposite situation.

An individual experiences severe chronic pain despite normal scans and medical investigations.

Someone develops phantom limb pain after amputation.

A person with fibromyalgia experiences widespread pain despite no obvious tissue damage.

An individual suffers debilitating migraines despite no visible injury.

In these situations, pain exists. Yet tissue damage may be minimal or absent. Again, pain cannot simply be explained as a direct readout of injury.

Something else is happening.


The Brain Is Not Reading Pain

A common misconception is that the brain acts like a computer reading incoming messages. The reality is far more sophisticated.

Modern neuroscience increasingly supports the idea that the brain functions as a prediction machine. Rather than passively waiting for information, the brain continuously asks:

“What is happening?”

“How dangerous is it?”

“What should I do about it?”

Pain appears to emerge from the brain’s attempt to answer these questions.

The human brain rapidly combines incoming sensory information with previous experiences, memory, learning, expectations, emotional state, beliefs, current stress levels, and environmental context before constructing the experience we call pain.

Pain is therefore not merely detected. Pain is actively constructed by the brain based upon incoming information, prior learning, emotional state, and context.


Why Context Matters

Imagine stepping on the same object under different circumstances.

Scenario One:

You are walking barefoot through your garden.

You step on a sharp object unexpectedly.

Pain is immediate.

Scenario Two:

You are undergoing a medical procedure.

You know discomfort is expected.

You trust the clinician.

The same level of stimulation may feel significantly less painful.

Scenario Three:

You are highly anxious, exhausted, sleep deprived, and worried about your health.

The exact same physical stimulus may feel dramatically worse.

The tissue has not changed.

The brain’s interpretation has changed.


The Emotional Brain and Pain

One of the greatest limitations of many pain models is that they largely ignore emotion. Pain is not simply sensory. Pain is profoundly emotional. Several brain regions contribute to the experience.

Somatosensory Cortex

Helps determine (1) Where the pain is (2) How intense it is

Insula

Processes bodily awareness and internal sensations.

Anterior Cingulate Cortex

Contributes to suffering and distress.

Amygdala

Assesses threat and danger.

Generates fear responses.

Prefrontal Cortex

Adds meaning, interpretation, planning, and decision making.

Pain emerges through the interaction of all these systems rather than from a single pain centre.

There is no single location in the brain where pain exists.

Pain is a network phenomenon.


Fear Can Increase Pain

Imagine touching a hot stove.

The immediate pain serves an adaptive purpose.

You withdraw your hand.

Problem solved.

However, if the nervous system begins associating many harmless experiences with danger, pain can become amplified.

The more fearful we become of pain:

  • The more we monitor it
  • The more we anticipate it
  • The more attention we give it

The more significant it can become.

This does not mean the pain is imaginary.

It means the nervous system is becoming increasingly protective.

In many chronic pain conditions, the alarm system becomes overly sensitive.

The danger detector becomes too good at its job.


What Chronic Pain Teaches Us

Acute pain protects us.

Chronic pain often reflects protection that has become excessive.

The nervous system learns.

The brain learns.

The body learns.

Neural pathways become strengthened through repetition.

Eventually the system may begin generating pain responses disproportionate to actual tissue damage.

This process is often referred to as:

  • Central sensitisation
  • Neural amplification
  • Pain sensitisation

The pain remains real.

The suffering remains real.

The underlying mechanisms, however, are different from those involved in acute injury.


A NeuroAffective-CBT Perspective

Within NeuroAffective-CBT, pain can be understood through the interaction between three continuously communicating systems:

Body

The body provides physiological information.

This includes:

  • Injury
  • Inflammation
  • Hormonal changes
  • Sleep quality
  • Nutrition
  • Energy availability
  • Physical conditioning

Brain

The brain interprets incoming information.

It generates predictions based upon:

  • Previous experiences
  • Memory
  • Learning
  • Core beliefs
  • Expectations

Affect

Affective systems shape emotional meaning.

These include:

  • Fear
  • Shame
  • Anxiety
  • Helplessness
  • Anger
  • Grief

Together these systems create the subjective experience we call pain.

Within NeuroAffective-CBT, emotional pain and physical pain are not viewed as entirely separate phenomena. Both involve physiological activation, affective meaning-making, cognitive interpretation, and behavioural responses. Clients frequently describe emotional suffering using physical language: a heavy chest, a knot in the stomach, emotional exhaustion, pressure, tension, emptiness, or feeling broken. Understanding pain therefore provides an important framework for understanding emotional suffering itself.


The Core Principle of NeuroAffective-CBT

The Body influences the Brain.

The Brain influences Affect.

Affect influences Behaviour.

Behaviour influences Physiology.

When any part of this system becomes dysregulated, suffering may emerge.

When all parts of the system are addressed together, healing becomes possible.

Why This Matters Clinically

Understanding pain differently changes how we approach treatment.

Rather than asking only:

“Where is the damage?”

We might also ask:

  • What is the nervous system trying to protect?
  • What role is stress playing?
  • What role is sleep playing?
  • What role is fear playing?
  • What role is emotional suppression playing?
  • What role is avoidance playing?
  • What role is physical deconditioning playing?
  • What role is chronic activation of threat systems playing?

These questions do not invalidate physical explanations.

They expand them.


Pain Is Real, Even When Scans Are Normal

One of the most harmful misconceptions encountered in clinical practice is the belief that normal scans mean symptoms are “all in the mind.”

Nothing could be further from the truth.

Modern neuroscience demonstrates that:

  • Pain is real.
  • The nervous system is real.
  • Brain-based processing is real.
  • Emotional amplification is real.
  • Sensitisation is real.

The absence of visible tissue damage does not invalidate suffering.

It simply means the explanation may be more complex than originally assumed.


The Future of Pain Science

Pain science continues to evolve.

Increasingly, researchers are recognising the importance of integrating:

  • Neuroscience
  • Psychology
  • Physiology
  • Immunology
  • Lifestyle medicine
  • Sleep science
  • Exercise science
  • Nutritional psychiatry
  • Metabolic psychiatry

into a more comprehensive understanding of human suffering.

Pain cannot be fully understood through tissue damage alone.

Nor can it be fully understood through psychology alone.

The future almost certainly lies in integration.

A NeuroAffective-CBT Formulation of Pain

From a NeuroAffective-CBT perspective, pain cannot be fully understood through a purely biomedical model, nor can it be adequately explained through a purely psychological framework. Rather, pain emerges from the dynamic interaction between physiological processes, affective systems, and cognitive interpretation. This perspective is consistent with the NA-CBT Bodyโ€“Brainโ€“Affect Triangle, which proposes that emotional and behavioural experiences arise from the continuous bidirectional communication between bodily states, brain-based processing, and affective meaning-making systems.

Within this framework, the body provides ongoing physiological information regarding injury, inflammation, fatigue, energy availability, sleep quality, nutrition, hormonal changes, and physical conditioning. The brain continuously interprets this information through the lens of prior learning, autobiographical memory, expectations, beliefs, and threat predictions. Simultaneously, affective systems assign emotional meaning to incoming experiences, influencing whether bodily sensations are perceived as manageable, threatening, overwhelming, or catastrophic.

Consequently, pain is not viewed as a simple readout of tissue damage but rather as a neuroaffective experience generated by the interaction of these multiple systems.

The Role of Threat Perception

One of the central assumptions within NA-CBT is that the nervous system is fundamentally organised around safety and survival. The brain continuously evaluates internal and external information to determine the level of threat present in any given situation.

When a stimulus is interpreted as dangerous, the nervous system may increase vigilance, muscular tension, autonomic arousal, and pain sensitivity. Conversely, when safety cues are present, physiological regulation improves, threat responses diminish, and pain intensity may decrease.

Importantly, threat perception is not determined solely by objective reality. It is influenced by previous experiences, trauma histories, attachment experiences, health beliefs, social context, and emotional states.

Two individuals may therefore experience the same physical injury in dramatically different ways depending upon how their nervous systems interpret and respond to the event.

Trauma, Emotional Learning, and Pain Amplification

Traumatic experiences can significantly alter the way the nervous system responds to future threats. Individuals who have experienced chronic adversity, abuse, neglect, medical trauma, bullying, or emotionally invalidating environments may develop heightened sensitivity within threat-detection systems.

Over time, the nervous system may become increasingly efficient at detecting danger, sometimes responding to relatively minor stimuli as though they represent significant threats.

Within the NA-CBT model, unresolved trauma memories may continue to influence present-day physiological and emotional reactions long after the original event has passed. Pain can therefore become linked not only to tissue-based signals but also to fear networks, emotional memories, learned associations, and protective behavioural patterns.

This perspective aligns with contemporary research demonstrating the involvement of the amygdala, anterior cingulate cortex, insula, hippocampus, and prefrontal regions in both pain processing and emotional regulation.

The Influence of Shame and Anxiety

NA-CBT places particular emphasis on the role of shame-based emotional schemas and chronic anxiety in maintaining emotional distress and self-sabotaging patterns.

Shame frequently operates as a hidden amplifier of suffering.

Individuals who carry longstanding beliefs such as:

  • “I am weak.”
  • “I should be coping better.”
  • “There must be something seriously wrong with me.”
  • “Nobody understands what I am going through.”

may experience increased emotional distress alongside physical symptoms.

Similarly, chronic anxiety can maintain heightened physiological arousal, increased muscle tension, sleep disruption, hypervigilance, and persistent monitoring of bodily sensations. These processes may inadvertently reinforce pain pathways and increase the perceived intensity of symptoms.

From a neuroaffective perspective, emotional suffering and physical suffering often become intertwined, creating self-reinforcing cycles that can be difficult to break without targeted intervention.

The Original TED Model: Tired, Exercise, and Diet

A central component of the NeuroAffective-CBT framework is the original TED model, which focuses on three fundamental physiological domains that frequently influence emotional wellbeing, stress tolerance, cognitive functioning, and pain perception:

Tiredness, Exercise, and Diet.

Within NA-CBT, TED is often conceptualised as an individual’s internal physiological coach. Before attempting to understand complex emotional reactions, trauma responses, self-sabotaging behaviours, or chronic distress, clinicians are encouraged to assess the extent to which these three biological domains may be influencing the individual’s current functioning.

Tiredness

Sleep deprivation and chronic fatigue can significantly alter the way the nervous system processes both emotional and physical experiences.

Research consistently demonstrates that insufficient sleep is associated with:

  • Increased pain sensitivity
  • Reduced emotional regulation
  • Heightened threat perception
  • Increased anxiety and irritability
  • Poorer stress tolerance
  • Reduced cognitive flexibility
  • Greater physiological arousal

From a neuroaffective perspective, an exhausted nervous system is often a more reactive nervous system.

Individuals experiencing chronic pain frequently report poor sleep quality, whilst poor sleep itself can increase pain intensity, creating a self-perpetuating cycle of distress and physiological dysregulation.

For this reason, improving sleep and recovery is often considered a foundational intervention within the NA-CBT model before attempting more intensive emotional processing work.

Exercise

Physical activity plays a critical role in both emotional and physiological regulation.

Regular movement influences multiple systems associated with pain modulation, including:

  • Endorphin release
  • Stress regulation
  • Neuroplasticity
  • Cardiovascular health
  • Inflammatory processes
  • Mood regulation
  • Self-efficacy and resilience

Importantly, exercise may also help challenge fear-avoidance patterns commonly observed in chronic pain conditions.

Many individuals gradually reduce activity levels because movement becomes associated with discomfort or fear of injury. Whilst avoidance may provide short-term relief, prolonged inactivity can contribute to deconditioning, increased vulnerability, reduced confidence, and further sensitisation of the nervous system.

Within NA-CBT, exercise is therefore viewed not simply as a physical intervention but also as a psychological and neurobiological regulator capable of influencing both mood and pain perception.

Diet

Nutrition provides the biological foundation upon which the brain and body operate.

Emerging evidence from nutritional psychiatry, metabolic psychiatry, and neuroscience increasingly suggests that dietary factors may influence emotional wellbeing, inflammation, energy production, cognitive functioning, and stress resilience.

Poor nutritional habits may contribute to:

  • Fatigue
  • Metabolic dysfunction
  • Increased inflammation
  • Blood sugar instability
  • Reduced concentration
  • Mood fluctuations
  • Poor recovery capacity

From an NA-CBT perspective, diet is not viewed through a restrictive or purely weight-focused lens. Rather, it is considered a crucial component of physiological regulation that may influence how effectively the nervous system responds to both emotional and physical stressors.

TED and Pain Perception

The relevance of the TED model to pain becomes increasingly apparent when viewed through a neuroaffective lens.

An individual who is:

  • Chronically sleep deprived,
  • Physically deconditioned,
  • Nutritionally dysregulated,

may experience a nervous system that is more reactive, more vigilant, and more sensitive to both internal and external stressors.

Consequently, pain intensity may increase even when tissue damage remains unchanged.

Conversely, improvements in sleep, physical conditioning, and nutritional stability may help reduce physiological stress, improve emotional regulation, increase resilience, and support healthier pain modulation pathways.

Within the NeuroAffective-CBT framework, TED therefore represents far more than a lifestyle intervention.

It represents a foundational physiological platform upon which emotional regulation, cognitive flexibility, behavioural change, trauma processing, and recovery can occur.

When individuals begin addressing tiredness, exercise, and diet simultaneously, they are often not simply improving their physical health. They are creating the biological conditions necessary for the nervous system to feel safer, more regulated, and less protective.

From this perspective, the TED model becomes directly relevant to understanding why some individuals remain trapped within cycles of chronic pain, emotional distress, and physiological dysregulation, whilst others gradually move towards recovery and resilience.

Metabolic Health, Ketogenic Therapies and Pain

Over recent years, growing attention has been directed towards the relationship between metabolic health, inflammation, brain function, emotional wellbeing, and chronic illness. Whilst traditionally associated with weight management or epilepsy treatment, ketogenic therapies are increasingly being investigated for their potential effects on neurological, psychiatric, and inflammatory conditions.

As discussed in a recent NeuroAffective-CBT article exploring ketogenic therapies and mental health, emerging research suggests that metabolic dysfunction may influence psychological wellbeing through mechanisms involving inflammation, mitochondrial function, oxidative stress, insulin resistance, and energy metabolism within the brain.

This perspective aligns closely with one of the central assumptions of the NA-CBT model: the brain does not function independently from the body. Physiological dysregulation may influence emotional wellbeing, whilst emotional distress may simultaneously influence physiological functioning.

The relevance of this emerging field to pain should not be underestimated.

Many chronic pain conditions are now recognised to involve not only structural or tissue-based factors but also inflammatory processes, autonomic dysregulation, altered stress responses, sleep disturbance, and changes in central nervous system functioning. Increasingly, researchers are exploring whether metabolic interventions may influence some of these mechanisms.

As stated in the recent NeuroAffective-CBT review of ketogenic therapies:

“The question is not whether ketogenic therapies represent a miracle cure. The question is whether some of the benefits reported by patients may be explained by improvements in physiological regulation, inflammation, energy metabolism, sleep, cognition, and emotional stability.”

This is an important distinction.

Within NA-CBT, ketogenic diets are not conceptualised as psychological treatments. Rather, they may represent one example of how physiological interventions can potentially influence the Bodyโ€“Brainโ€“Affect system.

For some individuals, improvements in metabolic health may be associated with:

  • Reduced systemic inflammation
  • Improved energy regulation
  • Enhanced cognitive clarity
  • Better sleep quality
  • Reduced emotional volatility
  • Improved stress tolerance

All of which may indirectly influence the experience of pain.

Further research is required before definitive conclusions can be reached. However, the growing field of metabolic psychiatry reinforces a principle that sits at the heart of NeuroAffective-CBTยฎ:

The body influences the brain. The brain influences affect. Affect influences behaviour. Behaviour influences physiology.

Understanding pain therefore requires us to look beyond symptoms alone and consider the broader physiological and emotional ecosystem within which those symptoms occur.

Towards an Integrated Understanding of Pain

The clinical implications of this model are significant.

Rather than asking solely:

Where is the injury?

NA-CBTยฎ encourages clinicians and individuals to also ask:

  • What is the nervous system trying to protect?
  • What emotional meanings have become attached to the symptoms?
  • What role is fear playing?
  • What role is shame playing?
  • What role is avoidance playing?
  • What role is trauma playing?
  • What role are sleep, nutrition, and physical conditioning playing?
  • What factors are maintaining the brain’s prediction that danger remains present?

These questions do not deny the reality of pain.

Instead, they acknowledge the complexity of human suffering and provide a broader framework for understanding why pain may persist long after tissue healing has occurred.

Ultimately, the NeuroAffective-CBTยฎ model views pain as a whole-person experience emerging from the continuous interaction between the body, brain, and affective systems. By addressing all three domains simultaneously, clinicians may be better positioned to help individuals reduce suffering, improve functioning, and develop a more integrated relationship with their physical and emotional experiences.


Final Thoughts

Perhaps the most important lesson from modern pain science is this:

Pain is not simply a signal travelling from the body to the brain.

Pain is a dynamic neurobiological experience emerging from the continuous interaction between bodily information, emotional states, prior learning, memory, beliefs, context, and prediction.

The body provides information.

The brain evaluates that information.

The affective system gives it meaning.

Together they create the conscious experience we call pain.

Understanding this complexity does not make pain less real.

If anything, it helps explain why pain can sometimes persist long after tissue healing has occurred, why emotions can influence symptoms, why stress can worsen discomfort, and why genuinely effective treatment often requires us to address the whole person rather than a single body part.

In many respects, pain may be one of the clearest demonstrations that human beings cannot be reduced to either mind or body alone.

We are, and always have been, an integrated neuroaffective system.


References

Apkarian, A.V., Baliki, M.N. and Geha, P.Y. (2009) ‘Towards a theory of chronic pain’, Progress in Neurobiology, 87(2), pp. 81โ€“97.

Atlas, L.Y. and Wager, T.D. (2012) ‘How expectations shape pain’, Neuroscience Letters, 520(2), pp. 140โ€“148.

Craig, A.D. (2003) ‘A new view of pain as a homeostatic emotion’, Trends in Neurosciences, 26(6), pp. 303โ€“307.

Eccleston, C. and Crombez, G. (1999) ‘Pain demands attention: A cognitive-affective model of the interruptive function of pain’, Psychological Bulletin, 125(3), pp. 356โ€“366.

Fields, H.L. (2004) ‘State-dependent opioid control of pain’, Nature Reviews Neuroscience, 5(7), pp. 565โ€“575.

Flor, H. (2003) ‘Cortical reorganisation and chronic pain: Implications for rehabilitation’, Journal of Rehabilitation Medicine, 35(S41), pp. 66โ€“72.

Gatchel, R.J., Peng, Y.B., Peters, M.L., Fuchs, P.N. and Turk, D.C. (2007) ‘The biopsychosocial approach to chronic pain: Scientific advances and future directions’, Psychological Bulletin, 133(4), pp. 581โ€“624.

LeDoux, J.E. (2015) Anxious: Using the Brain to Understand and Treat Fear and Anxiety. New York: Viking.

Melzack, R. (1999) ‘From the gate to the neuromatrix’, European Journal of Pain, 3(Suppl A), pp. 121โ€“126.

Melzack, R. and Wall, P.D. (1965) ‘Pain mechanisms: A new theory’, Science, 150(3699), pp. 971โ€“979.

Mirea, D. (2018) Describing NeuroAffective-CBTยฎ: An integrative model of psychological distress and emotional regulation. NeuroAffective-CBTยฎ. Available at: https://neuroaffectivecbt.com (Accessed: 1 June 2026).

Mirea, D. (2025) TED in NeuroAffective-CBTยฎ: An applied self-regulation framework for enhancing emotional wellbeing through sleep, movement and nutrition. NeuroAffective-CBTยฎ, 10 December. Available at: https://neuroaffectivecbt.com/2025/12/10/ted-in-neuroaffective-cbt-an-applied-self-regulation-framework-for-enhancing-emotional-well-being-through-sleep-movement-and-nutrition/ (Accessed: 1 June 2026).

Mirea, D. (2026) Could altering brain metabolism improve emotional wellbeing? Exploring ketogenic therapies through a NeuroAffective-CBTยฎ lens. NeuroAffective-CBTยฎ. Available at: https://neuroaffectivecbt.com (Accessed: 1 June 2026).

Moseley, G.L. and Butler, D.S. (2017) Explain Pain Supercharged. Adelaide: Noigroup Publications.

Nader, K. and Hardt, O. (2009) ‘A single standard for memory: The case for reconsolidation’, Nature Reviews Neuroscience, 10(3), pp. 224โ€“234.

Panksepp, J. (1998) Affective Neuroscience: The Foundations of Human and Animal Emotions. Oxford: Oxford University Press.

Schubiner, H. and Betzold, M. (2021) Unlearn Your Pain. Boulder, CO: Mind Body Publishing.

Tracey, I. and Mantyh, P.W. (2007) ‘The cerebral signature for pain perception and its modulation’, Neuron, 55(3), pp. 377โ€“391.

Turk, D.C. and Gatchel, R.J. (2018) Psychological Approaches to Pain Management: A Practitioner’s Handbook. 3rd edn. New York: Guilford Press.

Vlaeyen, J.W.S. and Linton, S.J. (2000) ‘Fear-avoidance and its consequences in chronic musculoskeletal pain’, Pain, 85(3), pp. 317โ€“332.

Wiech, K. (2016) ‘Deconstructing the sensation of pain: The influence of cognitive processes on pain perception’, Science, 354(6312), pp. 584โ€“587.

When Panic Attacks Go Beyond Panic Disorder: A NeuroAffective-CBT Perspective

Ioana Dulcu (April, 2026)
|The NeuroAffective-CBTยฎ Journal |ย 

A clinical story about how panic, shame, and physiological dysregulation interact and why stabilising physiological regulation can be the first step toward recovery.


Jenna’s story

When Jenna, a 26-year-old married woman, first arrived for therapy after the sudden onset of panic attacks, she dreaded that the conversation would revolve around her anxiety symptoms.

Naturally, she thought there would be questions about panic, about the frightening episode that had sent her to the emergency department, about what she had been thinking and feeling when the dizziness first appeared. In fact, she later admitted that she even anticipated she might throw up again.

What Jenna did not anticipate was that the assessment would begin somewhere more fundamental: examining the biological foundations that shape how the body responds to stress.

Sleep. Daily routines. Caffeine intake. Hydration. Movement. Even blood tests.

Like many people seeking help for panic attacks, Jenna assumed therapy would focus mainly on her thoughts, behaviours, and fears. Many people now research treatment options online before beginning therapy, and when they do, cognitive-behavioural methods such as interoceptive exposure are often presented as key evidence-based interventions, though they can also appear challenging at first.

What Jenna did not expect was that we would begin somewhere safer and more stabilising.

In the early sessions, rather than immediately exploring painful memories or emotional narratives, the work focused on regulation, restoring physiological balance through better sleep, movement, and nutritional habits.

The deeper personal stories would come later. Timing in NA-CBT is everything.

This approach reflects a core principle of NeuroAffective-CBT: when physiological arousal remains chronically elevated, emotional processing becomes far more difficult. Stabilising the body first often creates the conditions necessary for deeper psychological work to emerge safely.

Jenna had self-referred for therapy after a sudden episode of dizziness that appeared without warning two months earlier. The sensation was intense and frightening, accompanied by nausea, weakness in her knees, and a powerful fear that she might collapse or lose control. She went to the emergency department, where a full medical assessment was carried out. Neurological and vestibular causes were investigated, but no medical explanation was found.

Although the doctors reassured her that nothing serious had been detected, Jenna did not feel reassured. If anything, the uncertainty intensified her distress.

In the weeks that followed, panic attacks began to occur repeatedly. She developed a growing mistrust of her own body. Ordinary sensationsโ€”dizziness, nausea, shifts in breathingโ€”began to feel unpredictable and dangerous. Her attention became increasingly focused inward, scanning constantly for signs that another episode might occur.

Soon the panic spread into daily life. Jenna began avoiding leaving the house alone. Shopping trips felt unsafe unless her husband accompanied her. Her world gradually narrowed as the fear of bodily sensations expanded.

Vomiting episodes also began to appear, usually during periods of intense anticipatory anxiety. These episodes seemed to provide temporary relief from the overwhelming sensations in her body, but they reinforced her belief that something was fundamentally wrong internally.

At the same time, sleep became disrupted. Fatigue increased. The bodyโ€™s resilience decreased. The more exhausted she became, the more reactive her internal regulation felt.

During one of the early sessions, Jenna used a phrase that captured the essence of her distress:

โ€œMy body doesnโ€™t feel safe anymoreโ€.

At first glance, this presentation might seem like a relatively typical panic disorder with agoraphobic avoidance. But as the assessment unfolded, a deeper pattern began to emerge.

Jenna had been raised by a single mother together with three siblings. One memory stood out vividly. She was eight years old when her father left to work abroad and never returned. From that point forward, the emotional and practical responsibilities within the family shifted dramatically. Her mother, struggling with depression, found it difficult to maintain stability at home.

Jenna stepped in.

Even as a child, she assumed responsibilities that extended far beyond ordinary expectations. Helping her siblings became part of daily life, preparing lunches, supporting routines like cleaning and cooking and managing various responsibilities within the household.

Failure was not an option.

Getting things wrong felt dangerous. Someone might suffer if she did.

Looking back, Jenna described that period not as a conscious decision but as something she simply had to do. Over time, a quiet internal rule formed: if she remained alert enough, responsible enough, and careful enough, she could prevent things from going wrong.

The NeuroAffective-CBT formulation known as the Pendulum-Effect helps explain how such internal rules can shape coping patterns across many years.

At the centre of this pendulum system typically lies a powerful core affectโ€”often shame, guilt, or the fear of failing others. Around this core experience, a set of self-protective strategies gradually develops in an attempt to manage the internal threat it creates.

In Jennaโ€™s case, these strategies took three familiar forms. What once began as adaptive coping gradually evolved into self-sabotaging patterns that maintained the very distress they were originally designed to regulate.

One was overcompensation. She became highly vigilant, attentive to details, and constantly alert to potential problems. Missing something important felt unacceptable. Remaining on guard all the time seemed like the safest option.

Another strategy was avoidance. Situations that might create additional stress or draw attention toward her own needs were often postponed or abandoned. Investing time in herself, hobbies, rest, or personal interests, rarely felt justified.

Eventually, these cycles led to capitulation, moments when exhaustion and self-criticism took over. When she could not meet the impossible standards she had set for herself, the internal response was harsh: self-blame, guilt, and a sense that she was failing.

These strategies oscillated continuouslyโ€”overcompensation, avoidance, and capitulationโ€”like the movement of a pendulum. Each provided temporary relief from the underlying fear of getting things wrong, yet each also reinforced the deeper shame driving the system.

For many years, this pattern functioned quietly in the background of Jennaโ€™s life.

Until her body interrupted it.

When panic attacks appeared, the same pendulum dynamics intensified. Hypervigilance shifted toward internal sensations. Avoidance expanded into everyday life. Exhaustion and self-criticism deepened when symptoms seemed uncontrollable.

This was one of the reasons the therapist introduced the TED framework (Tiredโ€“Exerciseโ€“Diet) early in the treatment process. Lifestyle interventions in NeuroAffective-CBT are not simply recommendations for general wellbeing. They function as direct interventions within the pendulum system itself.

For someone whose life has been dominated by overcompensation and self-neglect, improving sleep, eating regularly, or creating space for physical movement becomes more than self-care. It becomes a challenge to the internal rule that personal needs must always come last.

In Jennaโ€™s case, stabilising her daily rhythms began to soften the relentless cycle of hypervigilance and exhaustion. Less fatigue meant less physiological reactivity. More predictable routines meant her internal regulation no longer had to remain constantly on guard.

Only once this stabilisation began did the deeper emotional narratives gradually come into view.

And only then did it become clear that Jennaโ€™s panic attacks were not simply about panic.

They were about a system that had spent many years trying not to fail anyone, until eventually the pendulum could no longer keep swinging.

To understand why this happens, we need to look more closely at how panic attacks actually develop inside the body.

Why Panic Attacks Are Sometimes Not Just About Panic

When people experience their first panic attack, it often feels as though something in the body has suddenly gone wrong.

The heart races. Breathing changes. The body may tremble or feel weak. Dizziness appears without warning. Nausea, heat, or a sense of losing control can follow within seconds. Because these sensations are so intense and unfamiliar, many people understandably assume they are experiencing a serious medical emergency.

Jennaโ€™s experience began in exactly this way.

The sudden dizziness that sent her to the emergency department felt like something catastrophic was happening inside her body. Even after medical tests ruled out neurological or vestibular causes, the feeling of danger did not disappear. The absence of a medical explanation did not bring relief, it created uncertainty.

And uncertainty is something the bodyโ€™s regulatory system does not tolerate well.

From the outside, panic attacks can appear sudden and unpredictable. Yet when we look more closely, they often emerge from an internal system that has been under pressure for a long time.

NeuroAffective-CBT approaches panic from the understanding that emotional distress rarely originates in thoughts alone. Instead, it arises from the interaction between three continuously communicating systems: the body, the brain, and affect, our emotional signalling system.

The body constantly sends signals about internal states, fatigue, hunger, hormonal shifts, blood sugar levels, sleep deprivation, muscle tension, and breathing patterns. The brain interprets these signals and attempts to predict whether the environment is safe or threatening. Affect provides the emotional tone that guides behaviour: fear, shame, anger, safety, and relief.

When these systems are balanced, signals move smoothly between them. The body senses changes, the brain interprets them accurately, and emotions guide appropriate responses.

But when the system becomes dysregulated, those signals can begin to amplify one another.

Fatigue may increase physiological sensitivity. Increased sensitivity can heighten attention toward bodily sensations. Heightened attention can make normal sensations feel unusual or threatening. Once the brain interprets those sensations as danger, the body responds with a rapid stress reaction.

At that point, the panic attack is already underway.

In Jennaโ€™s case, the first episode of dizziness acted like a spark in a system that was already vulnerable. Her autonomic state had spent many years in heightened vigilance, trying to anticipate problems, trying not to miss anything important, trying not to fail the responsibilities she had carried since childhood.

Hypervigilance can be a powerful survival strategy. It helps people remain alert, organised, and prepared. But when the body remains in this state for too long, it becomes increasingly sensitive to internal signals.

Even small fluctuations in breathing, blood pressure, or balance can suddenly feel alarming.

The body begins sending signals of danger not because there is a real external threat, but because the regulatory system has become overly reactive.

Once that cycle begins, panic attacks can develop quickly. The body senses something unusual, the brain interprets it as threat, and the emotional system amplifies the response.

This is why panic attacks often persist even when people know intellectually that nothing medically dangerous is happening.

The mind may understand that the body is safe, but the bodyโ€™s internal regulation has not yet learned that lesson.

And this is also why treatment that focuses only on thoughts may not always be sufficient.

If the body remains exhausted, overstimulated, sleep deprived, or metabolically unstable, it will continue sending signals that the brain interprets as danger. The emotional system then reacts accordingly.

In other words, the panic attack may be the final expression of a much larger regulatory imbalance.

This was the case for Jenna.

Her panic attacks were not simply the result of catastrophic thinking about bodily sensations. They were emerging from a system that had been operating under prolonged pressure, physiologically, emotionally, and psychologically.

Before the deeper emotional narratives could be explored, her body first needed something much more basic. It needed stabilisation.

And that is why, in the early sessions of therapy, the focus turned toward something Jenna had not expected to discuss at all, how she slept, how she ate, how she moved, and how her body had been carrying the weight of many years of responsibility.

The next step was learning something much harder: how to experience safety again inside her own body.

Learning to Trust the Body Again

Understanding the pendulum was an important step for Jenna.

But understanding alone was not enough.

Her mind could now see the pattern, how vigilance, avoidance, and self-criticism had reinforced one another for years, but her body was still reacting as if danger could appear at any moment. The dizziness, the nausea, the waves of anxiety still felt unpredictable.

And unpredictability is exactly what keeps the nervous system on guard. So the next phase of therapy focused on something very practical: helping Jenna experience safety again inside her own body. This required gently reversing several habits that had developed since the panic attacks began.

One of the most powerful of those habits was constant monitoring of internal sensations. Jenna had become extremely attentive to what was happening inside her body. Small changes in balance, breathing, or stomach sensations immediately triggered concern.

Ironically, this kind of monitoring often intensifies the very sensations people fear. The more attention we place on internal signals, the louder those signals can become.

Part of the work therefore involved gradually shifting Jennaโ€™s attention outward againโ€”toward activities, environments, and everyday experiencesโ€”rather than constantly scanning for signs of danger within her body.

At the same time, we began introducing graded exposure.

This did not mean forcing Jenna into overwhelming situations. Instead, it meant carefully testing the predictions her anxiety was making.

For example, one of Jennaโ€™s fears was leaving the house alone. Her mind predicted that if she went out without her husband, she might experience dizziness, lose control, or be unable to cope with panic. Rather than arguing with those predictions, therapy focused on gently testing them.

The first step was simply stepping outside alone for a short walk. Then walking a little farther. Then entering a shop independently. Each step was small enough to remain manageable, but meaningful enough to challenge the belief that she could not cope.

Each successful experience quietly sent a new message to her nervous system:

The body can feel uncomfortable and still be safe.

Another important part of this process involved what psychologists call interoceptive exposureโ€”learning to tolerate bodily sensations that had previously triggered panic.

For Jenna, sensations like dizziness or nausea had become signals of danger. The immediate instinct was to escape them as quickly as possible. In the past, vomiting had sometimes served as a way to relieve the sensation temporarily.

But the relief was short-lived. And each time the behaviour occurred, it reinforced the belief that the sensation itself was intolerable.

Instead, Jenna gradually practiced allowing these sensations to rise and fall without reacting to them. She noticed the dizziness, the changes in breathing, the slight waves of nausea, and remained with them long enough to observe that they eventually passed on their own.

This was not easy at first. But over time something important began to shift. The sensations that once felt catastrophic began to feel simply uncomfortable.

And uncomfortable is very different from dangerous.

The stabilising routines introduced earlier through the TED framework also played an important role during this phase. Better sleep meant her nervous system was less reactive. Regular meals and hydration helped prevent energy fluctuations that could mimic anxiety symptoms. Daily walking continued to strengthen her confidence in movement and balance.

Together, these changes created a more stable physiological foundation against which exposure could work effectively.

Little by little, Jenna began to experience something she had not felt in months. Moments of ordinary life. A walk outside without scanning for danger. A shopping trip completed alone.
An evening of sleep without waking in panic.

These were small victories, but they carried enormous meaning. Each one helped recalibrate a system that had been locked in fear. Gradually, the pendulum that once swung wildly between vigilance, avoidance, and collapse began to slow.

And with that slowing came something else Jenna had not felt in a long time: the sense that her body might once again be a place she could trust.

But the most important change was not simply the disappearance of panic.

The Moment Therapy Almost Changed Direction

Recovery from anxiety rarely follows a straight line.

For Jenna, the first months of therapy had already brought meaningful changes. The panic attacks had stopped. Vomiting episodes had reduced significantly. She was sleeping better, moving more, and gradually testing situations that had once felt impossible.

From the outside, it might have looked as though the hardest part was over.

But around the fifteenth session, something shifted.

During that week Jenna arrived at therapy noticeably distressed. The anxiety had intensified again, and the familiar sensations, dizziness, internal tension, waves of fear, felt closer to the surface than they had for several weeks. Although the panic attacks themselves had not returned, the emotional pressure she was experiencing was unmistakable.

Moments like this can be unsettling in therapy.

When symptoms reappear after progress has been made, it is easy for both therapist and client to wonder whether the improvement was temporary. The mind quickly begins asking uncomfortable questions: Is this working? Should something else be tried?

During that session we discussed the possibility of returning to her psychiatrist for a medication review. Jenna had already been taking escitalopram, and adjusting the medication was a reasonable option to consider if her distress continued to increase.

At first, the suggestion seemed as though it might signal a setback.

But something unexpected happened.

Instead of experiencing the conversation as a sign that therapy was failing, Jenna responded differently. The possibility of adjusting medication appeared to sharpen her awareness of how much progress she had already made. She realised that she did not want to retreat from the work she had been doing.

In that moment, something subtle but important shifted.

Rather than relying solely on external solutions, medication, reassurance, or avoidance, Jenna began to recognise her own role in the recovery process. The exposure exercises, the lifestyle changes, the effort to tolerate difficult sensations: these were not things being done to her. They were actions she had been taking herself.

Paradoxically, the conversation about medication strengthened her sense of responsibility and commitment.

In the sessions that followed, her engagement with the therapeutic work deepened noticeably. Exposure exercises became more consistent. She approached situations with greater confidence, even when anxiety appeared.

Instead of interpreting discomfort as a signal that something had gone wrong, she began to see it as part of the process of retraining her nervous system.

This is an important moment in many therapeutic journeys.

Recovery often accelerates when people move from seeing themselves as passive recipients of treatment to active participants in change. The focus shifts from โ€œHow do I make the anxiety disappear?โ€ to โ€œHow do I respond differently when anxiety appears?โ€

For Jenna, this shift marked the beginning of a more stable phase of recovery.

The pendulum that had once swung violently between vigilance, avoidance, and collapse was slowing. The sensations that once felt catastrophic were becoming manageable.

And perhaps most importantly, the sense that her body had betrayed her was gradually being replaced by something new: a quiet but growing confidence that she could handle what her body was feeling.

Closing Reflection

Jennaโ€™s story is not unusual. Many people who experience panic attacks assume the problem lies entirely in anxiety itself. They focus on the frightening sensations in the moment, the racing heart, the dizziness, and the feeling that something is about to go terribly wrong.

But panic often emerges at the intersection of several interacting systems: a body that has become physiologically over-reactive, an emotional system shaped by years of responsibility or vulnerability, and a mind that tries to make sense of sensations that suddenly feel unfamiliar.

When these systems fall out of balance, panic can become the language through which the nervous system signals distress. What Jennaโ€™s journey reminds us is that recovery does not always begin where people expect. Sometimes it begins with sleep, with nourishment, and with learning to move again without fear. Sometimes it begins with understanding the patterns that quietly shaped our responses to stress long before anxiety appeared.

And sometimes, as the pendulum slows, people discover something they had not realised they had lost: the ability to trust their own body again.

For clinicians, Jennaโ€™s case also illustrates an important point. Panic disorder can rarely be understood purely as a cognitive problem. When physiological instability, shame-based self-evaluation, and behavioural avoidance interact, treatment may need to address all three systems simultaneously.

For those experiencing panic themselves, the message is equally important.

The sensations may feel overwhelming. They may feel unpredictable. They may even feel dangerous.

But very often, they are the nervous systemโ€™s attempt to adapt.

And with the right support, the same system that once generated panic can learn something new: how to settle, how to rebalance, and how to move forward again.

This article does not aim to redefine the established understanding of panic disorder. Instead, it suggests that in some cases panic attacks may represent the final expression of earlier experiences marked by emotional neglect, which can contribute to broader regulatory imbalances involving physiological arousal, emotional signalling, and cognitive interpretation.

Traditional CBT offers well-established and effective models for the treatment of panic disorder. However, Jennaโ€™s story illustrates how panic symptoms can sometimes emerge from earlier life experiences marked by prolonged stress, hypervigilance, and role reversal within the family. Standard CBT approaches typically focus on the maintenance of panic symptoms in the present and may explore early experiences only when they are directly linked to current beliefs or behaviours.

Contemporary CBT protocols for panic disorder commonly incorporate excellent techniques such as cognitive restructuring and interoceptive exposure, originally developed within the Panic Control Treatment model of David H. Barlow and colleagues, alongside cognitive approaches such as the catastrophic misinterpretation model proposed by David M. Clark.

Over time, however, prolonged patterns of stress and self-regulation can contribute to dysregulation across physiological, affective, and cognitive systems. Restoring balance within this bodyโ€“brainโ€“affect network can gradually transform how anxiety is experienced and regulated.

In this sense, treating panic may sometimes require more than addressing fear itself, it may require accepting a painful history and helping the body, the mind, and the emotional system learn how to work together again.

Further reading:

Barlow, D.H. (2002) Anxiety and its disorders: The nature and treatment of anxiety and panic. 2nd edn. New York: Guilford Press.

Barlow, D.H., Craske, M.G. and Meadows, E.A. (2000) โ€˜Mastery of your anxiety and panic: Therapist guideโ€™, 3rd edn. New York: Oxford University Press.

Barlow, D.H., Gorman, J.M., Shear, M.K. and Woods, S.W. (2000) โ€˜Cognitive-behavioral therapy, imipramine, or their combination for panic disorder: A randomized controlled trialโ€™, Journal of the American Medical Association, 283(19), pp. 2529โ€“2536.

Barrett, L.F. (2017) โ€˜The theory of constructed emotion: An active inference account of interoception and categorizationโ€™, Social Cognitive and Affective Neuroscience, 12(1), pp. 1โ€“23.

Clark, D.M. (1986) โ€˜A cognitive approach to panicโ€™, Behaviour Research and Therapy, 24(4), pp. 461โ€“470.

Clark, D.M. (1997) โ€˜Panic disorder and social phobiaโ€™, in Clark, D.M. and Fairburn, C.G. (eds.) Science and practice of cognitive behaviour therapy. Oxford: Oxford University Press, pp. 121โ€“153.

Craske, M.G. and Barlow, D.H. (2007) โ€˜Mastery of your anxiety and panic: Therapist guideโ€™, 4th edn. New York: Oxford University Press.

Hirsch, C.R. and Mathews, A. (2019) โ€˜Approaching cognitive behaviour therapy for generalized anxiety disorder from a cognitive process perspectiveโ€™, Frontiers in Psychiatry, 10, p. 796.

McEwen, B.S. (2007) โ€˜Physiology and neurobiology of stress and adaptation: Central role of the brainโ€™, Physiological Reviews, 87(3), pp. 873โ€“904.

Mirea, D. (2018) NeuroAffective-CBTยฎ: Advancing the frontiers of cognitive-behavioural therapy. Available at: https://neuroaffectivecbt.com/2018/07/24/describing-na-cbt/ (Accessed: March 2026).

Mirea, D. (2019) The underlayers of NeuroAffective-CBTยฎ. Available at: https://neuroaffectivecbt.com/2018/10/19/the-underlayers-of-neuroaffective-cbt/ (Accessed: March 2026).

Mirea, D. (2025) The transdiagnostic application of NeuroAffective-CBTยฎ: A case study of chronic stress and burnout. Available at: https://neuroaffectivecbt.com (Accessed: March 2026).

National Institute for Health and Care Excellence (2020) Generalised anxiety disorder and panic disorder in adults: Management (CG113). London: NICE.

Confidentiality note: Jenna is a composite clinical vignette based on several cases. Identifying details have been altered to protect confidentiality.